PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31980614-5 2020 Displacement of a conserved tryptophan (W571) from its typical pocket in these Env mutants renders the Env insensitive to CD4 binding. verlukast 40-44 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 79-82 31980614-5 2020 Displacement of a conserved tryptophan (W571) from its typical pocket in these Env mutants renders the Env insensitive to CD4 binding. verlukast 40-44 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 103-106 31980614-6 2020 These results reveal the critical function of W571 as a conformational switch in Env allostery and receptor-mediated viral entry and provide insights on Env conformation that are relevant for vaccine design. verlukast 46-50 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 81-84 31980614-6 2020 These results reveal the critical function of W571 as a conformational switch in Env allostery and receptor-mediated viral entry and provide insights on Env conformation that are relevant for vaccine design. verlukast 46-50 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 153-156