PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 610003-5 1977 Isolation of tissue microsomes with Tris buffer, EDTA and the protease inhibitor phenylmethylsulfonylfluoride (PMSF), conditions which preserve the receptor molecules optimally, yielded about 50% of the tissue toxin-sites, 5% of the protein, 4% of the ATPase and less than 2% of the acetylcholinesterase (AChE). Phenylmethylsulfonyl Fluoride 111-115 acetylcholinesterase (Cartwright blood group) Homo sapiens 283-303 610003-5 1977 Isolation of tissue microsomes with Tris buffer, EDTA and the protease inhibitor phenylmethylsulfonylfluoride (PMSF), conditions which preserve the receptor molecules optimally, yielded about 50% of the tissue toxin-sites, 5% of the protein, 4% of the ATPase and less than 2% of the acetylcholinesterase (AChE). Phenylmethylsulfonyl Fluoride 111-115 acetylcholinesterase (Cartwright blood group) Homo sapiens 305-309 11275256-5 2000 The antibodies recognised AchE and were capable of hydrolysing acetylthiocholine and the larger butyrylthiocholine substrate, and were inactivated by phenylmethylsulphonyl fluoride (PMSF), indicating a serine residue in the active site. Phenylmethylsulfonyl Fluoride 150-180 acetylcholinesterase (Cartwright blood group) Homo sapiens 26-30 11275256-5 2000 The antibodies recognised AchE and were capable of hydrolysing acetylthiocholine and the larger butyrylthiocholine substrate, and were inactivated by phenylmethylsulphonyl fluoride (PMSF), indicating a serine residue in the active site. Phenylmethylsulfonyl Fluoride 182-186 acetylcholinesterase (Cartwright blood group) Homo sapiens 26-30 10340306-0 1999 Phenylmethylsulfonyl fluoride inhibitory effects on acetylcholinesterase of brain and muscle. Phenylmethylsulfonyl Fluoride 0-29 acetylcholinesterase (Cartwright blood group) Homo sapiens 52-72 10340306-1 1999 Differential inhibition of brain versus peripheral acetylcholinesterase (AChE) by phenylmethylsulfonyl fluoride (PMSF) suggested that PMSF might preferentially inhibit different AChE molecular forms. Phenylmethylsulfonyl Fluoride 82-111 acetylcholinesterase (Cartwright blood group) Homo sapiens 51-71 10340306-1 1999 Differential inhibition of brain versus peripheral acetylcholinesterase (AChE) by phenylmethylsulfonyl fluoride (PMSF) suggested that PMSF might preferentially inhibit different AChE molecular forms. Phenylmethylsulfonyl Fluoride 82-111 acetylcholinesterase (Cartwright blood group) Homo sapiens 73-77 10340306-1 1999 Differential inhibition of brain versus peripheral acetylcholinesterase (AChE) by phenylmethylsulfonyl fluoride (PMSF) suggested that PMSF might preferentially inhibit different AChE molecular forms. Phenylmethylsulfonyl Fluoride 82-111 acetylcholinesterase (Cartwright blood group) Homo sapiens 178-182 10340306-1 1999 Differential inhibition of brain versus peripheral acetylcholinesterase (AChE) by phenylmethylsulfonyl fluoride (PMSF) suggested that PMSF might preferentially inhibit different AChE molecular forms. Phenylmethylsulfonyl Fluoride 113-117 acetylcholinesterase (Cartwright blood group) Homo sapiens 51-71 10340306-1 1999 Differential inhibition of brain versus peripheral acetylcholinesterase (AChE) by phenylmethylsulfonyl fluoride (PMSF) suggested that PMSF might preferentially inhibit different AChE molecular forms. Phenylmethylsulfonyl Fluoride 113-117 acetylcholinesterase (Cartwright blood group) Homo sapiens 73-77 10340306-1 1999 Differential inhibition of brain versus peripheral acetylcholinesterase (AChE) by phenylmethylsulfonyl fluoride (PMSF) suggested that PMSF might preferentially inhibit different AChE molecular forms. Phenylmethylsulfonyl Fluoride 134-138 acetylcholinesterase (Cartwright blood group) Homo sapiens 51-71 10340306-1 1999 Differential inhibition of brain versus peripheral acetylcholinesterase (AChE) by phenylmethylsulfonyl fluoride (PMSF) suggested that PMSF might preferentially inhibit different AChE molecular forms. Phenylmethylsulfonyl Fluoride 134-138 acetylcholinesterase (Cartwright blood group) Homo sapiens 73-77 10340306-1 1999 Differential inhibition of brain versus peripheral acetylcholinesterase (AChE) by phenylmethylsulfonyl fluoride (PMSF) suggested that PMSF might preferentially inhibit different AChE molecular forms. Phenylmethylsulfonyl Fluoride 134-138 acetylcholinesterase (Cartwright blood group) Homo sapiens 178-182 10340306-9 1999 These results suggest that PMSF inhibition of AChE is a consequence of a selective inhibition of membrane-associated forms and that the apparent brain selectivity is related to the greater fraction of membrane-associated AChE in brain. Phenylmethylsulfonyl Fluoride 27-31 acetylcholinesterase (Cartwright blood group) Homo sapiens 46-50 10340306-9 1999 These results suggest that PMSF inhibition of AChE is a consequence of a selective inhibition of membrane-associated forms and that the apparent brain selectivity is related to the greater fraction of membrane-associated AChE in brain. Phenylmethylsulfonyl Fluoride 27-31 acetylcholinesterase (Cartwright blood group) Homo sapiens 221-225 10942971-9 1998 PMSF, a specific inhibitor for serine proteases and mammalian acetylcholinesterase, completely inhibited the formation of flumazenil -acid and the flumazenil methylester at a concentration of 100 microM. Phenylmethylsulfonyl Fluoride 0-4 acetylcholinesterase (Cartwright blood group) Homo sapiens 62-82 4306345-0 1969 The action of phenylmethylsulfonyl fluoride on human acetylcholinesterase, chymotyrpsin and trypsin. Phenylmethylsulfonyl Fluoride 14-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-73