PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12225969-10 2002 In the presence of 20 microM TSH, an 88% reduction in terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling (TUNEL)-positive cells was observed in serum-starved (3 h) 3T3-L1 preadipocytes as well as a 93% reduction in the level of cleaved activated caspase 3. deoxyuridine triphosphate 107-111 caspase 3 Mus musculus 271-280 28973639-6 2017 Moreover, the activation of p53 and Bax with the inhibition of Bcl-2 might be the reason for the upregulation of caspase-3 in the apoptosis, as detected by TdT-mediated dUTP nick-end labeling assay in the testes induced by 1,2-DCE. deoxyuridine triphosphate 169-173 caspase 3 Mus musculus 113-122 11356696-5 2001 Furthermore, caspase-3 mutant female mice possessed aberrant atretic follicles containing granulosa cells that failed to be eliminated by apoptosis, as confirmed by TUNEL (terminal deoxynucleotidyl transferase-mediated deoxy-UTP nick end labeling) analysis of DNA cleavage and 4",6-diamidino-2-phenylindole staining of nuclear morphology (pyknosis). deoxyuridine triphosphate 219-228 caspase 3 Mus musculus 13-22 9531309-4 1998 Treatment of C3Heb/FeJ mice with 700 mg/kg galactosamine (Gal) and 100 microg/kg Salmonella abortus equi ET increased caspase 3-like protease activity (Asp-Val-Glu-Asp-substrate) by 1730 +/- 140% at 6 h. There was a parallel enhancement of apoptosis (assessed by DNA fragmentation ELISA and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay). deoxyuridine triphosphate 338-342 caspase 3 Mus musculus 118-127 19390003-8 2009 In contrast, there was an increase in TdT-mediated dUTP nick end label-positive nuclei in the denervated muscle of wild-type compared with caspase-3-knockout mice. deoxyuridine triphosphate 51-55 caspase 3 Mus musculus 139-148 27267546-9 2016 Renal caspase-3 activity was decreased in Cirp(-/-) mice compared with wild-type mice after renal ischemia-reperfusion, which corresponded to the reduction of apoptotic cells determined by terminal deoxynucleotidyl transferase dUTP nick-end labeling assay. deoxyuridine triphosphate 227-231 caspase 3 Mus musculus 6-15 22328080-6 2012 This rapid downregulation of caspase-3 activity was confirmed by immunostaining for cleaved caspase-3 and terminal deoxynucleotidyl transferase dUTP-mediated nick-end label staining. deoxyuridine triphosphate 144-148 caspase 3 Mus musculus 29-38 21898491-5 2011 The inability of Tnc(-/-) mice to express Tnc significantly reduced the levels of active caspase-3/transferase-mediated dUTP nick end-labeling (TUNEL) apoptotic markers and enhanced the expression of the proliferation cell nuclear antigen (PCNA) after liver IRI. deoxyuridine triphosphate 120-124 caspase 3 Mus musculus 89-98 19863544-3 2010 Cleavage of caspase-3 and increased terminal deoxynucleotidyl transferase (TdT)-mediated deoxyuridine triphosphate (dUTP) nick-end-labeling (TUNEL)-positive cells in D-gal-treated old mice were inhibited by PSPC, which might be attributed to its antioxidant property. deoxyuridine triphosphate 116-120 caspase 3 Mus musculus 12-21 27644033-6 2016 Rutin treatment resulted in the downregulation of caspase-3 expression in a reduced number of positive cells under terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling assay, and also the improved survival of neurons. deoxyuridine triphosphate 162-166 caspase 3 Mus musculus 50-59 14604764-2 2003 We examined the relationship between activation of caspase-3 and programmed cell death (PCD) during forebrain development of various mouse strains (129/Sv, ICR, C57L/B6, and CBA) using terminal deoxytransferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) and immunostaining with antiserum against the caspase-3 (anti-m3D175) cleavage site. deoxyuridine triphosphate 220-245 caspase 3 Mus musculus 51-60 18372426-6 2008 Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling revealed no significant differences in the number of apoptotic cells between Sod1(-/-) and wild-type mice, and activated caspase-3 could not be detected in the retina of Sod1(-/-) mice. deoxyuridine triphosphate 47-51 caspase 3 Mus musculus 191-200 14679058-10 2003 Only a small proportion of intra-islet caspase-3 cells showed apoptotic nuclei judged by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL). deoxyuridine triphosphate 136-140 caspase 3 Mus musculus 39-48 12802593-17 2003 During this late stage, only a proportion of caspase-3-positive cells contained apoptotic nuclei, as judged by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling (TUNEL). deoxyuridine triphosphate 158-162 caspase 3 Mus musculus 45-54