PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31377845-0 2020 DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools. deoxyuridine triphosphate 77-81 dCTP pyrophosphatase 1 Homo sapiens 0-6 31377845-3 2020 Here, we identify a central role for DCTPP1 in the homeostasis of dCTP, dTTP and dUTP. deoxyuridine triphosphate 81-85 dCTP pyrophosphatase 1 Homo sapiens 37-43 31377845-4 2020 Nucleotide pools and the dUTP/dTTP ratio are severely altered in DCTPP1-deficient cells, which exhibit an accumulation of uracil in genomic DNA, the activation of the DNA damage response and both a mitochondrial and nuclear hypermutator phenotype. deoxyuridine triphosphate 25-29 dCTP pyrophosphatase 1 Homo sapiens 65-71