PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11112443-6 2000 Finally, recombinant expression of hGIIF sPLA(2) in Escherichia coli shows that the enzyme is Ca(2+)-dependent, maximally active at pH 7-8, and hydrolyzes phosphatidylglycerol versus phosphatidylcholine with a 15-fold preference. Phosphatidylglycerols 155-175 phospholipase A2 group IIA Homo sapiens 41-48 22173044-5 2012 RESULTS: BAL sPLA2 enzyme activity was markedly elevated in ARDS samples relative to healthy subjects when measured by ex vivo hydrolysis of both phosphatidylglycerol (PG) and phosphatidylcholine (PC). Phosphatidylglycerols 146-166 phospholipase A2 group IIA Homo sapiens 13-18 22173044-5 2012 RESULTS: BAL sPLA2 enzyme activity was markedly elevated in ARDS samples relative to healthy subjects when measured by ex vivo hydrolysis of both phosphatidylglycerol (PG) and phosphatidylcholine (PC). Phosphatidylglycerols 168-170 phospholipase A2 group IIA Homo sapiens 13-18 22173044-6 2012 Enzyme immunoassay identified increased PLA2G2A protein in the ARDS BAL fluid, which was strongly correlated with the sPLA2 enzyme activity against PG. Phosphatidylglycerols 148-150 phospholipase A2 group IIA Homo sapiens 40-47 22173044-6 2012 Enzyme immunoassay identified increased PLA2G2A protein in the ARDS BAL fluid, which was strongly correlated with the sPLA2 enzyme activity against PG. Phosphatidylglycerols 148-150 phospholipase A2 group IIA Homo sapiens 118-123 22173044-8 2012 Furthermore, the sPLA2 enzyme activity against PG and PC ex vivo correlated with the BAL recovery of in vivo PG and PC, respectively, and also correlated with the altered distribution of the large and small surfactant aggregates. Phosphatidylglycerols 47-49 phospholipase A2 group IIA Homo sapiens 17-22 16461407-5 2006 By using phosphatidylcholine/phosphatidylglycerol model systems, we show that local enrichment of anionic lipids into fluid domains triggers PLA2-IIA activity. Phosphatidylglycerols 29-49 phospholipase A2 group IIA Homo sapiens 141-145 15173620-5 2004 sPLA2 activity is monitored using a fluorimetric assay that measures the continuous calcium-dependent formation of albumin-bound pyrene fatty acid from the sn-2 position of phosphatidylglycerol. Phosphatidylglycerols 173-193 phospholipase A2 group IIA Homo sapiens 0-5 2758074-1 1989 The specificity of snake venom phospholipase A2(PLA2) towards a number of phospholipid (PL) substrates, e. g., phosphatidylcholine (PC), phosphatidylglycerol (PG), phosphatidylethanolamine (PE) and phosphatidylinositol (PI) organized in Triton X-100 mixed micelles, liposomes and proteoliposomes was studied. Phosphatidylglycerols 137-157 phospholipase A2 group IIA Homo sapiens 48-52 2758074-1 1989 The specificity of snake venom phospholipase A2(PLA2) towards a number of phospholipid (PL) substrates, e. g., phosphatidylcholine (PC), phosphatidylglycerol (PG), phosphatidylethanolamine (PE) and phosphatidylinositol (PI) organized in Triton X-100 mixed micelles, liposomes and proteoliposomes was studied. Phosphatidylglycerols 159-161 phospholipase A2 group IIA Homo sapiens 48-52 27871839-4 2017 CL/PG ratio is different in polluted than in unspoiled soils and it was hypothesized that it is connected with the activity of the membranelytic enzymes from the phospholipase A2 class (PLA2) as it was proved that persistent soil pollutants can activate PLA2. Phosphatidylglycerols 3-5 phospholipase A2 group IIA Homo sapiens 186-190 27871839-4 2017 CL/PG ratio is different in polluted than in unspoiled soils and it was hypothesized that it is connected with the activity of the membranelytic enzymes from the phospholipase A2 class (PLA2) as it was proved that persistent soil pollutants can activate PLA2. Phosphatidylglycerols 3-5 phospholipase A2 group IIA Homo sapiens 254-258 10760469-3 2000 This specificity is due to selective penetration of the highly cationic human sPLA(2)50%) phospholipid hydrolysis was observed and this was confirmed by electrospray mass spectrometry that allowed the identification of several molecular species of phosphatidylglycerol as the targets for hydrolysis. Phosphatidylglycerols 248-268 phospholipase A2 group IIA Homo sapiens 78-84