PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18071320-9 2008 Collectively, this study suggests COX-2 induction and synthesis of L-PGDS-derived, PPARgamma-activating PGs as a decisive target by which several chemotherapeutics induce apoptosis. Phosphatidylglycerols 104-107 peroxisome proliferator activated receptor gamma Homo sapiens 83-92 23943857-8 2013 Together, our data demonstrate a proapoptotic mechanism of celecoxib involving initial upregulation of COX-2 and PPARgamma and a subsequent nuclear translocation of PPARgamma by COX-2-dependent PGs. Phosphatidylglycerols 194-197 peroxisome proliferator activated receptor gamma Homo sapiens 165-174 23220503-8 2013 Together, our data show a novel proapoptotic mechanism of cannabidiol involving initial upregulation of COX-2 and PPAR-gamma and a subsequent nuclear translocation of PPAR-gamma by COX-2-dependent PGs. Phosphatidylglycerols 197-200 peroxisome proliferator activated receptor gamma Homo sapiens 167-177 19015962-10 2009 CONCLUSION: This study demonstrates COX-2 induction and synthesis of L-PGDS-derived, PPARgamma-activating PGs as a possible mechanism of apoptosis by MA. Phosphatidylglycerols 106-109 peroxisome proliferator activated receptor gamma Homo sapiens 85-94 11104898-3 2000 Very recent studies clarified that P53 independent expression of p21 and gadd 45, activation of PPARgamma are involved in antitumor mechanism of these PGs. Phosphatidylglycerols 151-154 peroxisome proliferator activated receptor gamma Homo sapiens 96-105 15322177-2 2004 The facts that phthalate ester metabolites, like endogenous PGs, are peroxisome proliferator-activated receptor (PPAR) agonists, and that PPARgamma agonists induce lymphocyte apoptosis suggest that phthalate esters are immunosuppressants that could act together with PGs to modulate early B cell development. Phosphatidylglycerols 60-63 peroxisome proliferator activated receptor gamma Homo sapiens 113-117