PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7957532-2	1994	Up to a rate of infusion of esmolol of 500 micrograms.kg-1 BW.min-1 there was a maximal beta 1-receptor occupancy of 84.7% while beta 2-receptor occupancy was below the detection limit; confirming the beta 1 selectivity of esmolol.	esmolol	28-35	CD59 molecule (CD59 blood group)	Homo sapiens	62-67	
7957532-2	1994	Up to a rate of infusion of esmolol of 500 micrograms.kg-1 BW.min-1 there was a maximal beta 1-receptor occupancy of 84.7% while beta 2-receptor occupancy was below the detection limit; confirming the beta 1 selectivity of esmolol.	esmolol	223-230	CD59 molecule (CD59 blood group)	Homo sapiens	62-67	
1972334-2	1990	Twenty patients scheduled for aorto-coronary bypass grafting suffering from tachycardia (heart rate (HR) greater than 100 beat min-1) were treated by infusion of esmolol, an ultra-short acting, selective beta 1-blocker.	esmolol	162-169	CD59 molecule (CD59 blood group)	Homo sapiens	127-132	
1681842-2	1991	A mean infusion rate of esmolol 50.5 micrograms kg-1 min-1 resulted in a decrease in mean arterial pressure to 63 mm Hg and heart rate to 99 beat min-1 and was associated with excellent surgical conditions.	esmolol	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	53-58	
1681842-2	1991	A mean infusion rate of esmolol 50.5 micrograms kg-1 min-1 resulted in a decrease in mean arterial pressure to 63 mm Hg and heart rate to 99 beat min-1 and was associated with excellent surgical conditions.	esmolol	24-31	CD59 molecule (CD59 blood group)	Homo sapiens	146-151	
8484510-9	1993	During one propofol anesthetic, an esmolol infusion (100 micrograms.kg-1 x min-1) was started 10 min before stimulation to determine whether this agent would blunt the pupillary response.	esmolol	35-42	CD59 molecule (CD59 blood group)	Homo sapiens	75-80	
3719434-4	1986	The benzoylcholine hydrolysis rates in the plasma of ten patients who received an esmolol infusion of 500 micrograms.kg-1.min-1 for 4 minutes were 58.6 +/- 6.2 mumol.hr-1.ml-1 (mean +/- SE) before and 55.1 +/- 6.6 mumol.hr-1.ml-1 after the infusion.	esmolol	82-89	CD59 molecule (CD59 blood group)	Homo sapiens	122-127	
3526984-9	1986	Infusion of esmolol at 200 micrograms X kg-1 X min-1 prevented tachycardia in response to intubation.	esmolol	12-19	CD59 molecule (CD59 blood group)	Homo sapiens	47-52	
9549747-7	1998	One patient required three intravenous doses of esmolol (10mg each) for a heart rate in excess of 100 beats.min-1.	esmolol	48-55	CD59 molecule (CD59 blood group)	Homo sapiens	108-113	
15966380-3	2005	METHODS: Propranolol (n=22) or esmolol (n= 29) was given intravenously when the heart rate was above 100 beats x min(-1) during emergence from anesthesia.	esmolol	31-38	CD59 molecule (CD59 blood group)	Homo sapiens	113-119	
15966380-6	2005	The total dose of esmolol was 32.8 +/- 16.2 mg, which decreased the heart rate significantly from 110.0+/-13.9 to 84.9+/-10.7 beats x min(-1).	esmolol	18-25	CD59 molecule (CD59 blood group)	Homo sapiens	134-140	
11736772-2	2001	Thirty-one patients received an infusion of esmolol 0-300 microg x kg(-1) x min(-1) and 37 patients comprised the control group.	esmolol	44-51	CD59 molecule (CD59 blood group)	Homo sapiens	76-82