PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29534875-0 2018 Esculetin suppresses tumor growth and metastasis by targeting Axin2/E-cadherin axis in colorectal cancer. esculetin 0-9 cadherin 1 Mus musculus 68-78 29534875-6 2018 Here, esculetin (ES), a coumarin, was found to have the most potential effects on both beta-catenin-responsive transcriptional and E-cadherin promoter activities. esculetin 6-15 cadherin 1 Mus musculus 131-141 29534875-6 2018 Here, esculetin (ES), a coumarin, was found to have the most potential effects on both beta-catenin-responsive transcriptional and E-cadherin promoter activities. esculetin 17-19 cadherin 1 Mus musculus 131-141 29534875-8 2018 Mechanistically, Axin2 suppression by ES contributed to E-cadherin-mediated Wnt signaling inhibition. esculetin 38-40 cadherin 1 Mus musculus 56-66 29534875-10 2018 Collectively, these findings suggest that targeting the Axin2/E-cadherin axis by ES may be an attractive therapeutic strategy for the treatment of metastatic CRC. esculetin 81-83 cadherin 1 Mus musculus 62-72