PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32301145-8	2020	Only esculetin decreased AR, galactitol, and advanced glycated end products levels in lenses.	esculetin	5-14	aldo-keto reductase family 1 member B1	Rattus norvegicus	25-27	
26902086-0	2016	Esculetin, a Coumarin Derivative, Inhibits Aldose Reductase Activity in vitro and Cataractogenesis in Galactose-Fed Rats.	esculetin	0-9	aldo-keto reductase family 1 member B1	Rattus norvegicus	43-59	
26902086-4	2016	In this study, the potential beneficialeffects of esculetin on lenticular aldose reductase were investigated in galactose-fed (GAL) rats, an animal model of sugar cataracts.	esculetin	50-59	aldo-keto reductase family 1 member B1	Rattus norvegicus	74-90	
26902086-8	2016	Esculetin reduced rat lens aldose reductase (RLAR) activity in vitro, and esculetin treatment significanty inhibited lens opacity, as well as morphological alterations, such as swelling, vacuolation and liquefaction of lens fibers,via the inhibition of aldose reductase in the GAL rats.	esculetin	0-9	aldo-keto reductase family 1 member B1	Rattus norvegicus	27-43	
26902086-8	2016	Esculetin reduced rat lens aldose reductase (RLAR) activity in vitro, and esculetin treatment significanty inhibited lens opacity, as well as morphological alterations, such as swelling, vacuolation and liquefaction of lens fibers,via the inhibition of aldose reductase in the GAL rats.	esculetin	74-83	aldo-keto reductase family 1 member B1	Rattus norvegicus	253-269