PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31211861-8	2019	Furthermore, we examined the effect of esculetin on NF-kappaB pathway by detecting the expression levels of NF-kappaB p65, p-p65 and IkappaBalpha using western blot analysis.	esculetin	39-48	RELA proto-oncogene, NF-kB subunit	Homo sapiens	118-121	
31211861-9	2019	Esculetin treatment suppressed the histamine-induced p-p65 expression and p-IkappaBalpha degradation.	esculetin	0-9	RELA proto-oncogene, NF-kB subunit	Homo sapiens	55-58	
30171828-4	2018	The levels of NFkB p65 decreased in the nucleus at high esculetin concentration treatments for long times (19 h), concomitantly increasing the levels of anti-inflammatory NFkB p50 in the nucleus.	esculetin	56-65	RELA proto-oncogene, NF-kB subunit	Homo sapiens	19-22	
27756327-3	2016	METHODS: The cytotoxicity of esculetin was determined in PANC-1, MIA PaCa-2 and AsPC-1 cell lines; followed by an inspection of intracellular levels of ROS and its associated transcription factor, p65-NF-kappaB.	esculetin	29-38	RELA proto-oncogene, NF-kB subunit	Homo sapiens	197-200	
27756327-8	2016	A notable decrease was observed in intracellular ROS and protein levels of p65-NF-kappaB in PANC-1 cells on esculetin treatment.	esculetin	108-117	RELA proto-oncogene, NF-kB subunit	Homo sapiens	75-78