PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9261338-1 1997 It was clearly demonstrated that two structurally different inhibitors of 5-lipoxygenase (5-LPO) metabolism (leukotriene synthesis), i.e. MK-886 and esculetin, when combined with transforming growth factor-beta 1 (TGF-beta 1), significantly enhanced the differentiation but did not change proliferation (i.e. cell number and cell cycle parameters) of human leukemia HL-60 cells in vitro. esculetin 149-158 lactoperoxidase Homo sapiens 92-95