PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30387134-0 2019 Toll-like receptor 3 agonist poly I:C reinforces the potency of cytotoxic chemotherapy via the TLR3-UNC93B1-IFN-beta signaling axis in paclitaxel-resistant colon cancer. Carbon 36-37 interferon beta 1 Homo sapiens 108-116 21952237-8 2011 Poly(I:C) was also shown to induce interferon (IFN)-beta mRNA expression in trophoblasts. Carbon 7-8 interferon beta 1 Homo sapiens 35-56 29962372-7 2018 HOSCN decreased polyI:C-induced apoptosis and the expression levels of IFNB1, IFNL1, IFNL2 and IFNL3 mRNAs. Carbon 3-4 interferon beta 1 Homo sapiens 71-76 27468646-4 2016 CAM treatment led to a significant reduction in poly I:C- and RSV-mediated IL-8, CCL5, IFN-beta and -lambda production. Carbon 0-1 interferon beta 1 Homo sapiens 87-95 25822580-4 2015 Co-stimulation with IFN-gamma and the TLR3 ligand poly (I:C) synergistically increased the expression of IFN-beta, IL-6, IL-8, and human beta-defensin-2 in NHEKs compared with poly (I:C) or IFN-gamma alone. Carbon 0-1 interferon beta 1 Homo sapiens 105-113 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 interferon beta 1 Homo sapiens 138-146 34695651-5 2021 PU.1 expression also primes the cells to develop a strong immune response against the dsRNA virus mimic polyinosinic:polycytidylic acid (poly I:C) by significantly up-regulating Interferon-beta (14.9 fold change with p-value <0.0001). Carbon 144-145 interferon beta 1 Homo sapiens 178-193 16399790-9 2006 Pretreatment with wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase, was able to abate the effect of DE(as) on poly(I:C)-induced IFN-beta expression. Carbon 134-135 interferon beta 1 Homo sapiens 145-153 1660913-2 1991 We show that Poly I:C-induced antiviral activity is completely abrogated by antibodies to interferon-beta (IFN-beta) whereas antibodies to other interferons or to other cytokines have no effect. Carbon 20-21 interferon beta 1 Homo sapiens 90-105 1660913-2 1991 We show that Poly I:C-induced antiviral activity is completely abrogated by antibodies to interferon-beta (IFN-beta) whereas antibodies to other interferons or to other cytokines have no effect. Carbon 20-21 interferon beta 1 Homo sapiens 107-115 17669408-9 2008 Treatment of FTEC with TLR3 agonist poly(I:C) resulted in increased expression of interleukin-8, tumor-necrosis factor alpha, human beta-defensin 2, interferon beta, and interferon stimulated genes myxovirus resistance gene 1, 2",5"-oligoadenylate synthetase, and protein kinase R. Additionally, FTEC exposed to poly(I:C) also resulted in the induction of TLR2, TLR3, and TLR7. Carbon 16-17 interferon beta 1 Homo sapiens 149-164