PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33408784-0	2021	Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission.	azelastine	19-29	ADP ribosylation factor 1	Homo sapiens	83-87	
33408784-8	2021	ARF1 was identified as a direct target of azelastine.	azelastine	42-52	ADP ribosylation factor 1	Homo sapiens	0-4	
33408784-11	2021	Mechanistically, azelastine bound to Thr-48 in ARF1 and repressed its activity, decreasing Drp1 phosphorylation.	azelastine	17-27	ADP ribosylation factor 1	Homo sapiens	47-51