PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1680533-0 1991 Effect of azelastine and ketotifen on the bronchial and skin responses to platelet-activating factor in humans. azelastine 10-20 PCNA clamp associated factor Homo sapiens 74-100 9431823-0 1997 Inhibitory effect of azelastine hydrochloride on synthesis and release of platelet activating factor from human alveolar macrophages. azelastine 21-45 PCNA clamp associated factor Homo sapiens 74-100 9431823-1 1997 The effect of azelastine hydrochloride (azelastine) on synthesis and release of platelet activating factor (PAF) in alveolar macrophages obtained from asthmatic and non-asthmatic subjects was examined. azelastine 14-38 PCNA clamp associated factor Homo sapiens 80-106 9431823-1 1997 The effect of azelastine hydrochloride (azelastine) on synthesis and release of platelet activating factor (PAF) in alveolar macrophages obtained from asthmatic and non-asthmatic subjects was examined. azelastine 14-38 PCNA clamp associated factor Homo sapiens 108-111 9431823-1 1997 The effect of azelastine hydrochloride (azelastine) on synthesis and release of platelet activating factor (PAF) in alveolar macrophages obtained from asthmatic and non-asthmatic subjects was examined. azelastine 14-24 PCNA clamp associated factor Homo sapiens 80-106 9431823-1 1997 The effect of azelastine hydrochloride (azelastine) on synthesis and release of platelet activating factor (PAF) in alveolar macrophages obtained from asthmatic and non-asthmatic subjects was examined. azelastine 14-24 PCNA clamp associated factor Homo sapiens 108-111 9431823-4 1997 PAF activity released from alveolar macrophages (AMs) from asthmatics without preincubation of azelastine was 15.97 [2.17] (mean [SD], ng/10(7) cells) in supernatants and 42.52 [10.16] in cell pellets. azelastine 95-105 PCNA clamp associated factor Homo sapiens 0-3 9431823-5 1997 After preincubation with 10(-8), 10(-6), and 10(-4) M of azelastine, PAF activity reduced to 10.71 [2.73] (mean [SD], ng/10(7) cells), 7.86 [0.94], and 3.52 [0.31] in the supernatants, and 35.58 [7.37], 21.57 [4.36], and 14.77 [0.99] (n = 15) in the cell pellets, respectively. azelastine 57-67 PCNA clamp associated factor Homo sapiens 69-72 9431823-6 1997 PAF activity in non-asthmatic subjects without preincubation of azelastine was 8.55 [1.16] (mean [SD], ng/10(7) cells) in supernatants and 32.64 [3.37] in cell pellets. azelastine 64-74 PCNA clamp associated factor Homo sapiens 0-3 9431823-7 1997 After preincubation with 10(-8), 10(-6), and 10(-4) M of azelastine, PAF activity reduced to 6.68 [0.78] (mean [SD], ng/10(7) cells), 4.47 [0.51], and 2.97 [0.36] in the supernatants, and 29.53 [3.75], 14.78 [1.95], and 6.16 [0.55] (n = 20) in the cell pellets, respectively. azelastine 57-67 PCNA clamp associated factor Homo sapiens 69-72 9431823-8 1997 Our results showed that preincubation with azelastine caused a dose-dependent inhibition of intra- and extracellular PAF activity from asthmatic and non-asthmatic macrophages in the same manner. azelastine 43-53 PCNA clamp associated factor Homo sapiens 117-120 1680533-1 1991 In a randomized, double-blind placebo-controlled study we investigated the effect of single oral doses of 8 mg azelastine and 2 mg ketotifen on the immediate response to platelet-activating factor (PAF) inhalation and to increasing doses of PAF injected intradermally. azelastine 111-121 PCNA clamp associated factor Homo sapiens 170-196 1680533-1 1991 In a randomized, double-blind placebo-controlled study we investigated the effect of single oral doses of 8 mg azelastine and 2 mg ketotifen on the immediate response to platelet-activating factor (PAF) inhalation and to increasing doses of PAF injected intradermally. azelastine 111-121 PCNA clamp associated factor Homo sapiens 198-201 1645817-2 1991 Aminophylline (20 micrograms/ml) and Isoproterenol (10 nM) inhibited PAF (3 X 10(-8) M)-induced eosinophil chemotaxis nearly 30%, whereas no inhibitory effects were observed by Dexamethasone (0.1 microM), Tranilast, Ketotifen or Azelastine. azelastine 229-239 PCNA clamp associated factor Homo sapiens 69-72