PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20691680-1 2010 UDP-glucose dehydrogenase (UGDH) catalyzes oxidation of UDP-glucose to yield UDP-glucuronic acid, a precursor of hyaluronic acid (HA) and other glycosaminoglycans (GAGs) in extracellular matrix. Hyaluronic Acid 113-128 UDP-glucose 6-dehydrogenase Homo sapiens 0-25 28496038-3 2017 Our experimental results indicate that methylmercury induces the expression of hyaluronan in cultured human microvascular endothelial cells and pericytes through the induction of expressed UDP-glucose dehydrogenase and hyaluronan synthase 2, respectively. Hyaluronic Acid 79-89 UDP-glucose 6-dehydrogenase Homo sapiens 189-214 31123107-7 2019 Further, we found a significant increase of UDP-glucose 6-dehydrogenase, generating a building block for biosynthesis of hyaluronan, another crucial component of the vocal fold lamina propria In line with this result, hyaluronan levels were significantly increased because of cigarette smoke exposure. Hyaluronic Acid 121-131 UDP-glucose 6-dehydrogenase Homo sapiens 44-71 31123107-7 2019 Further, we found a significant increase of UDP-glucose 6-dehydrogenase, generating a building block for biosynthesis of hyaluronan, another crucial component of the vocal fold lamina propria In line with this result, hyaluronan levels were significantly increased because of cigarette smoke exposure. Hyaluronic Acid 218-228 UDP-glucose 6-dehydrogenase Homo sapiens 44-71 24145036-1 2013 UDP-glucose dehydrogenase (UGDH) provides precursors for steroid elimination, hyaluronan production, and glycosaminoglycan synthesis. Hyaluronic Acid 78-88 UDP-glucose 6-dehydrogenase Homo sapiens 0-25 24145036-1 2013 UDP-glucose dehydrogenase (UGDH) provides precursors for steroid elimination, hyaluronan production, and glycosaminoglycan synthesis. Hyaluronic Acid 78-88 UDP-glucose 6-dehydrogenase Homo sapiens 27-31 21576248-9 2011 Targeting Sp1 and UGDH with specific siRNAs also lowered hyaluronan synthase-1 (HAS-1) and HAS-2 levels and reduced hyaluronan accumulation in orbital fibroblasts. Hyaluronic Acid 57-67 UDP-glucose 6-dehydrogenase Homo sapiens 18-22 21576248-11 2011 These high UGDH levels may underlie susceptibility of the orbit to localized overproduction of hyaluronan in Graves disease. Hyaluronic Acid 95-105 UDP-glucose 6-dehydrogenase Homo sapiens 11-15 20691680-1 2010 UDP-glucose dehydrogenase (UGDH) catalyzes oxidation of UDP-glucose to yield UDP-glucuronic acid, a precursor of hyaluronic acid (HA) and other glycosaminoglycans (GAGs) in extracellular matrix. Hyaluronic Acid 113-128 UDP-glucose 6-dehydrogenase Homo sapiens 27-31 20691680-1 2010 UDP-glucose dehydrogenase (UGDH) catalyzes oxidation of UDP-glucose to yield UDP-glucuronic acid, a precursor of hyaluronic acid (HA) and other glycosaminoglycans (GAGs) in extracellular matrix. Hyaluronic Acid 130-132 UDP-glucose 6-dehydrogenase Homo sapiens 0-25 20691680-1 2010 UDP-glucose dehydrogenase (UGDH) catalyzes oxidation of UDP-glucose to yield UDP-glucuronic acid, a precursor of hyaluronic acid (HA) and other glycosaminoglycans (GAGs) in extracellular matrix. Hyaluronic Acid 130-132 UDP-glucose 6-dehydrogenase Homo sapiens 27-31 16002992-1 2005 UDP-glucose dehydrogenase (UGDH) catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is required in liver for the excretion of toxic compounds, and for the biosynthesis of complex carbohydrates, such as hyaluronan, in many cell types. Hyaluronic Acid 221-231 UDP-glucose 6-dehydrogenase Homo sapiens 0-25 16418163-9 2006 In human smooth muscle cells the overexpression of xUGDH or endogenous abrogation of UGDH modulated hyaluronan synthesis specifically. Hyaluronic Acid 100-110 UDP-glucose 6-dehydrogenase Homo sapiens 52-56 16495656-1 2006 The enzyme UDP-glucose dehydrogenase (UGDH) catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynthesis of complex carbohydrates such as hyaluronan in many cell types, and is required for detoxification of toxic compounds in the liver. Hyaluronic Acid 181-191 UDP-glucose 6-dehydrogenase Homo sapiens 11-36 16495656-1 2006 The enzyme UDP-glucose dehydrogenase (UGDH) catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynthesis of complex carbohydrates such as hyaluronan in many cell types, and is required for detoxification of toxic compounds in the liver. Hyaluronic Acid 181-191 UDP-glucose 6-dehydrogenase Homo sapiens 38-42 19244115-1 2009 UDP-glucose dehydrogenase (UGDH) oxidizes UDP-glucose to UDP-glucuronate, an essential precursor for production of hyaluronan (HA), proteoglycans, and xenobiotic glucuronides. Hyaluronic Acid 115-125 UDP-glucose 6-dehydrogenase Homo sapiens 0-25 19244115-1 2009 UDP-glucose dehydrogenase (UGDH) oxidizes UDP-glucose to UDP-glucuronate, an essential precursor for production of hyaluronan (HA), proteoglycans, and xenobiotic glucuronides. Hyaluronic Acid 115-125 UDP-glucose 6-dehydrogenase Homo sapiens 27-31 19244115-1 2009 UDP-glucose dehydrogenase (UGDH) oxidizes UDP-glucose to UDP-glucuronate, an essential precursor for production of hyaluronan (HA), proteoglycans, and xenobiotic glucuronides. Hyaluronic Acid 127-129 UDP-glucose 6-dehydrogenase Homo sapiens 0-25 19244115-1 2009 UDP-glucose dehydrogenase (UGDH) oxidizes UDP-glucose to UDP-glucuronate, an essential precursor for production of hyaluronan (HA), proteoglycans, and xenobiotic glucuronides. Hyaluronic Acid 127-129 UDP-glucose 6-dehydrogenase Homo sapiens 27-31 16002992-1 2005 UDP-glucose dehydrogenase (UGDH) catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is required in liver for the excretion of toxic compounds, and for the biosynthesis of complex carbohydrates, such as hyaluronan, in many cell types. Hyaluronic Acid 221-231 UDP-glucose 6-dehydrogenase Homo sapiens 27-31 2287590-3 1990 UDP-glucose dehydrogenase is particularly important in oxidizing UDP-glucose to UDP-glucuronic acid, the building block of hyaluronic acid and chondroitin sulfates. Hyaluronic Acid 123-138 UDP-glucose 6-dehydrogenase Homo sapiens 0-25 9737970-1 1998 The enzyme UDP-glucose dehydrogenase (Udpgdh) (EC 1.1.1.22) converts UDP-glucose to UDP-glucuronate, a critical component of the glycosaminoglycans, hyaluronan, chondroitin sulfate, and heparan sulfate. Hyaluronic Acid 149-159 UDP-glucose 6-dehydrogenase Homo sapiens 11-36 9737970-1 1998 The enzyme UDP-glucose dehydrogenase (Udpgdh) (EC 1.1.1.22) converts UDP-glucose to UDP-glucuronate, a critical component of the glycosaminoglycans, hyaluronan, chondroitin sulfate, and heparan sulfate. Hyaluronic Acid 149-159 UDP-glucose 6-dehydrogenase Homo sapiens 38-44 7525525-13 1994 Since UDPGD activity is involved in hyaluronan synthesis, it is proposed that joint cavitation is facilitated by a rise in local hyaluronan concentration in an area of tissue where cohesion is dependent on the interaction between cellular CD44 and extracellular hyaluronan. Hyaluronic Acid 36-46 UDP-glucose 6-dehydrogenase Homo sapiens 6-11 7525525-13 1994 Since UDPGD activity is involved in hyaluronan synthesis, it is proposed that joint cavitation is facilitated by a rise in local hyaluronan concentration in an area of tissue where cohesion is dependent on the interaction between cellular CD44 and extracellular hyaluronan. Hyaluronic Acid 129-139 UDP-glucose 6-dehydrogenase Homo sapiens 6-11 1329776-9 1992 High UDPGD activity probably reflects a preferential ability to synthesize glycosaminoglycans, including hyaluronan. Hyaluronic Acid 105-115 UDP-glucose 6-dehydrogenase Homo sapiens 5-10 33572239-0 2021 Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells. Hyaluronic Acid 156-166 UDP-glucose 6-dehydrogenase Homo sapiens 26-51 33572239-15 2021 However, UGDH knockdown contributes to epirubicin resistance, which might be associated with increases in the expression, deposition and catabolism of hyaluronan. Hyaluronic Acid 151-161 UDP-glucose 6-dehydrogenase Homo sapiens 9-13 31308490-0 2020 UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Hyaluronic Acid 38-53 UDP-glucose 6-dehydrogenase Homo sapiens 0-27 32214199-0 2020 Correction: UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Hyaluronic Acid 50-65 UDP-glucose 6-dehydrogenase Homo sapiens 12-39 32175296-1 2020 UDP-glucose dehydrogenase (UGDH) encodes an oxidoreductase that converts two successive oxidations of UDP-glucose to produce UDP-glucuronic acid, a key component in the synthesis of several polysaccharides such as glycosaminoglycan and the disaccharide hyaluronic acid. Hyaluronic Acid 253-268 UDP-glucose 6-dehydrogenase Homo sapiens 0-25 32175296-1 2020 UDP-glucose dehydrogenase (UGDH) encodes an oxidoreductase that converts two successive oxidations of UDP-glucose to produce UDP-glucuronic acid, a key component in the synthesis of several polysaccharides such as glycosaminoglycan and the disaccharide hyaluronic acid. Hyaluronic Acid 253-268 UDP-glucose 6-dehydrogenase Homo sapiens 27-31