PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8997260-11 1996 TGF-beta 1 also promoted secretion of glycosaminoglycans into culture medium by BASMC with a preferential increase in hyaluronan secretion (4.5-fold) after 24 h. Latent TGF-beta (0.89 +/- 0.06 ng/ml) was also detected in conditioned medium from cultured BASMC, and TGF-beta 1 expression was demonstrated with RNA extracts from BASMC. Hyaluronic Acid 118-128 transforming growth factor beta 1 Bos taurus 0-10 19195913-4 2009 The purpose of this study was to determine the ability of hyaluronan in the pericellular matrix to modulate the chondrocyte responses to BMP-7 or TGF-beta1. Hyaluronic Acid 58-68 transforming growth factor beta 1 Bos taurus 146-155 19195913-7 2009 RESULTS: The disruption of the hyaluronan-dependent pericellular matrix of chondrocytes resulted in diminished nuclear translocation of endogenous Smad1 and Smad4 in response to BMP-7; however, the nuclear translocation of Smad2 and Smad4 in these matrix-depleted chondrocytes in response to TGF-beta1 was not diminished. Hyaluronic Acid 31-41 transforming growth factor beta 1 Bos taurus 292-301 8997260-11 1996 TGF-beta 1 also promoted secretion of glycosaminoglycans into culture medium by BASMC with a preferential increase in hyaluronan secretion (4.5-fold) after 24 h. Latent TGF-beta (0.89 +/- 0.06 ng/ml) was also detected in conditioned medium from cultured BASMC, and TGF-beta 1 expression was demonstrated with RNA extracts from BASMC. Hyaluronic Acid 118-128 transforming growth factor beta 1 Bos taurus 0-8 1910291-2 1991 This paper provides evidence that chondrocytes synthesize the appropriate proteoglycan matrix under TGF-beta 1 stimulation: (i) there is a coordinated increase in hyaluronic acid and proteoglycan monomer synthesis, (ii) link-stable proteoglycan aggregates are assembled, (ii) the hybrid chondroitin sulfate/keratan sulfate monomeric species is synthesized, and (iv) there is an increase in protein core synthesis. Hyaluronic Acid 163-178 transforming growth factor beta 1 Bos taurus 100-110