PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20299009-1 2010 The objective was to assess outcomes of IFNgamma-priming upon macrophage activation by the synovial macromolecule high molecular weight hyaluronan [HMW-HA] in the context of rheumatoid arthritis inflammation. Hyaluronic Acid 136-146 cilia and flagella associated protein 97 Homo sapiens 148-151 20709728-3 2010 We observed that binding of high-molecular-weight hyaluronan (HMW-HA) to its cognate receptor CD44 within caveolin-enriched microdomains (CEM) enhances human pulmonary EC barrier function. Hyaluronic Acid 50-60 cilia and flagella associated protein 97 Homo sapiens 62-65 20042707-4 2010 High-molecular-weight hyaluronan (HMW-HA, approximately 1x10(6) Da) decreased HABP2 protein expression in human pulmonary microvascular ECs and decreased purified HABP2 enzymatic activity, whereas low-molecular-weight HA (LMW-HA, approximately 2500 Da) increased these activities. Hyaluronic Acid 22-32 cilia and flagella associated protein 97 Homo sapiens 34-37 20482991-6 2010 Subsequently sulphated hyaluronan and chitosan were used to form PEM on PLLA that was covalently modified with HMW PEI. Hyaluronic Acid 23-33 cilia and flagella associated protein 97 Homo sapiens 111-114 16806998-2 2006 Intra-articular injection of high molecular weight hyaluronic acid (HMW-HA) has been used as viscosupplementation for knee OA but its effect on synoviocytes remains undisclosed. Hyaluronic Acid 51-66 cilia and flagella associated protein 97 Homo sapiens 68-71 19325714-1 2009 PURPOSE: The aim of this study was to investigate high molecular weight hyaluronan (HMW-HA) protection on human corneal epithelial (HCE) cells against ultraviolet B (UVB) radiation-induced toxic effects. Hyaluronic Acid 72-82 cilia and flagella associated protein 97 Homo sapiens 84-87 18806267-1 2008 Hyaluronan, a widely distributed component of the extracellular matrix, exists in a high molecular weight (native) form and lower molecular weight form (HMW- and LMW-HA, respectively). Hyaluronic Acid 0-10 cilia and flagella associated protein 97 Homo sapiens 153-156 34769349-2 2021 Additionally, high-molecular-weight hyaluronic acid (HMW-HA) was often used clinically to treat OA. Hyaluronic Acid 36-51 cilia and flagella associated protein 97 Homo sapiens 53-56 25684737-1 2015 It has been proved that high molecular weight hyaluronic acid (HMW-HA, 1x10(6) Da) micro-strips on titanium (Ti) surface can elongate the human vascular endothelial cell (EC) morphology, subsequently enhance endothelial extracellular matrix (ECM) deposition in our previous work. Hyaluronic Acid 46-61 cilia and flagella associated protein 97 Homo sapiens 63-66 12452440-0 2002 The hyaluronan-binding serine protease from human plasma cleaves HMW and LMW kininogen and releases bradykinin. Hyaluronic Acid 4-14 cilia and flagella associated protein 97 Homo sapiens 65-68 34550425-1 2022 PURPOSE: To assess the efficacy and safety of intravesical instillation of high molecular weight sodium hyaluronate (HMW-HA) for the treatment of radiation-induced cystitis. Hyaluronic Acid 97-115 cilia and flagella associated protein 97 Homo sapiens 117-120 34992208-6 2022 We demonstrated that the FSAP inhibitor, high-molecular-weight hyaluronan (HMW-HA), enhanced the pro-angiogenic vascular factors, improved the integrity of brain blood barrier, and promoted newly formed cerebral microvessels in the ischemic penumbra, consequently improving neurological function. Hyaluronic Acid 63-73 cilia and flagella associated protein 97 Homo sapiens 75-78 34248816-3 2021 High-molecular-weight (hMW) hyaluronic acid (HA) is an ideal vehicle for IT Gd due to its viscous and adhesive properties. Hyaluronic Acid 28-43 cilia and flagella associated protein 97 Homo sapiens 23-26 35625538-5 2022 This study aimed to verify whether high-molecular-hyaluronic acid (HMW-HA) serves as a cryoprotectant when preserving human mesenchymal stem cells (hMSCs) to reduce the DMSO concentration in the cryopreservation medium. Hyaluronic Acid 50-65 cilia and flagella associated protein 97 Homo sapiens 67-70 34016170-2 2021 The current study was performed to determine whether pretreatment of MSC EV with high molecular weight hyaluronic acid (HMW HA) would increase the therapeutic potency of MSC EV in severe bacterial pneumonia. Hyaluronic Acid 103-118 cilia and flagella associated protein 97 Homo sapiens 120-123 32799851-1 2020 BACKGROUND: To compare intra-articular (IA) knee injections of a cross-linked high-molecular-weight hyaluronic acid (HMW-HA) with a linear low-molecular weight HA (LMW-HA) in terms of pain and functional improvement among knee osteoarthritis (OA) patients. Hyaluronic Acid 100-115 cilia and flagella associated protein 97 Homo sapiens 117-120 33517896-3 2021 High molecular weight hyaluronan (HMW-HA) is a glycosaminoglycan sugar, which is a physiological constituent of the lung extracellular matrix and has notable anti-inflammatory and hydrating properties. Hyaluronic Acid 22-32 cilia and flagella associated protein 97 Homo sapiens 34-37 32643955-1 2020 Aim: To examine the time-to-total knee replacement (TKR) surgery among patients with high-concentration nonavian high-molecular-weight hyaluronan injection (HMW-HA) compared with those without HA injections. Hyaluronic Acid 135-145 cilia and flagella associated protein 97 Homo sapiens 157-160 32530559-1 2020 BACKGROUND: Hyaluronic acid (HA) is major physiological component of the extracellular matrix, which, in its high molecular weight form (HMW-HA) has anti-inflammatory properties. Hyaluronic Acid 12-27 cilia and flagella associated protein 97 Homo sapiens 137-140 31067702-3 2019 High molecular weight hyaluronan (HMW-HA) has previously been shown to exert protective effects on PM2.5-induced acute lung injury and inflammation. Hyaluronic Acid 22-32 cilia and flagella associated protein 97 Homo sapiens 34-37 32218833-3 2020 Hyaluronans have different cellular functions depending on their molecular weights and high molecular weight-hyaluronan (HMW-HA) exhibits anti-inflammatory effects. Hyaluronic Acid 0-11 cilia and flagella associated protein 97 Homo sapiens 121-124 32218833-3 2020 Hyaluronans have different cellular functions depending on their molecular weights and high molecular weight-hyaluronan (HMW-HA) exhibits anti-inflammatory effects. Hyaluronic Acid 109-119 cilia and flagella associated protein 97 Homo sapiens 121-124 30884980-2 2019 This study aims to update the prior study results to include only the high concentration non-avian high molecular weight hyaluronan (HMW-HA) injectables using data from recent years. Hyaluronic Acid 121-131 cilia and flagella associated protein 97 Homo sapiens 133-136 26447809-2 2015 We have previously reported that high molecular weight hyaluronan (HMW-HA), a major glycosaminoglycan in the body, promotes rapid signal transduction in human pulmonary microvascular endothelial cells (HPMVEC) leading to barrier enhancement. Hyaluronic Acid 55-65 cilia and flagella associated protein 97 Homo sapiens 67-70 27212811-2 2016 Hyaluronan (HA) in its high molecular weight form (HMW-HA) shows anti-inflammatory responses in contrast to low and medium molecular weight HA (LMW-HA and MMW-HA). Hyaluronic Acid 0-10 cilia and flagella associated protein 97 Homo sapiens 51-54 25983734-1 2015 We previously reported the anti-allergic effect of high molecular weight form of hyaluronic acid (HMW-HA). Hyaluronic Acid 81-96 cilia and flagella associated protein 97 Homo sapiens 98-101 25126764-2 2014 Low molecular weight hyaluronan (LMW HA) derived from the degradation of high molecular weight hyaluronan (HMW HA) is suggested to activate cells involved in wound healing through interaction with HA receptors. Hyaluronic Acid 21-31 cilia and flagella associated protein 97 Homo sapiens 107-110 25126764-2 2014 Low molecular weight hyaluronan (LMW HA) derived from the degradation of high molecular weight hyaluronan (HMW HA) is suggested to activate cells involved in wound healing through interaction with HA receptors. Hyaluronic Acid 95-105 cilia and flagella associated protein 97 Homo sapiens 107-110