PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32130660-11	2020	After treatment with si-LINC01234 or miR-193a-5p mimic, EC cells (Eca-109 and EC9706) exhibited cyclinD1 and Bcl-2 downregulation, and caspase-3, p21, Bax and cleaved caspase-3 upregulation.	Silicon	21-23	caspase 3	Homo sapiens	135-144	
15309413-2	2004	Exposure of the myocytes to SI (simulated ischaemia - energy depletion induced by KCN and 2-deoxy- D-glucose) reduced cell viability, as measured by the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) assay, and stimulated apoptosis as evidenced by caspase-3 activation and poly(ADP-ribose) polymerase (PARP) cleavage.	Silicon	28-30	caspase 3	Homo sapiens	269-278	
28013316-10	2016	Furthermore, the up-regulative effects of miR-149-5p suppression on the phosphorylated form of Fas-associated via death domain (p-FADD), caspase-8, caspase-2, caspase-3, and the cleaved forms of these caspases were abrogated by si-FASLG.	Silicon	60-62	caspase 3	Homo sapiens	159-168	
25957141-6	2015	At higher concentrations, Si increased caspase-3, as well as TBARS, LDH, DNA fragmentation, and TNF-alpha releases.	Silicon	26-28	caspase 3	Homo sapiens	39-48	
15309413-16	2004	Our results suggest that p38 has a pro-apoptotic role while JNK phosphorylation is protective in our cell model and that these kinases act via caspase-3 to prevent or promote cell survival in response to SI/R-induced injury.	Silicon	204-206	caspase 3	Homo sapiens	143-152	
34677776-11	2022	Moreover, SI-WmiRs inhibited pro-apoptotic BAX, Caspase 3 and Caspase 8 gene expression and protein levels to prevent apoptosis of UV-stressed HaCaT cells.	Silicon	10-12	caspase 3	Homo sapiens	48-57