PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8393868-2	1993	The kinetic parameters, Km and Vmax, for MAO-B-catalyzed oxidation of MPTP to the corresponding species MPDP+ were found to be 0.194 mM and 0.335 microM/min, respectively.	1-methyl-4-phenyl-2,3-dihydropyridinium	104-109	monoamine oxidase B	Homo sapiens	41-46	
2788162-1	1989	Kinetic deuterium isotope effects for the noncompetitive, intermolecular monoamine oxidase B-catalyzed oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to the corresponding 1-methyl-4-phenyl-2,3-dihydropyridinium species MPDP+ were found to be 3.55 on Vmax and 8.01 on Vmax/Km with MPTP-6,6-d2 as the deuterated substrate.	1-methyl-4-phenyl-2,3-dihydropyridinium	189-228	monoamine oxidase B	Homo sapiens	73-92	
2788162-1	1989	Kinetic deuterium isotope effects for the noncompetitive, intermolecular monoamine oxidase B-catalyzed oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to the corresponding 1-methyl-4-phenyl-2,3-dihydropyridinium species MPDP+ were found to be 3.55 on Vmax and 8.01 on Vmax/Km with MPTP-6,6-d2 as the deuterated substrate.	1-methyl-4-phenyl-2,3-dihydropyridinium	237-242	monoamine oxidase B	Homo sapiens	73-92	
3091760-8	1986	The ability of monoamine oxidase inhibitors to prevent MPTP toxicity is related to the metabolism of MPTP by monoamine oxidase B, probably extraneuronally in glia, to produce MPDP+ and subsequently MPP+.	1-methyl-4-phenyl-2,3-dihydropyridinium	175-180	monoamine oxidase B	Homo sapiens	109-128	
3485542-1	1986	The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its deuterated analogues were oxidized to their corresponding dihydropyridinium species (MPDP+) by preparations of pure human liver MAO B:monoclonal antibody complex to investigate the mechanism of MPTP activation.	1-methyl-4-phenyl-2,3-dihydropyridinium	160-164	monoamine oxidase B	Homo sapiens	203-208	
3874094-3	1985	MPDP+, MPTP, and MPP+, but not PTP, were found to be irreversible inhibitors of MAO B.	1-methyl-4-phenyl-2,3-dihydropyridinium	0-5	monoamine oxidase B	Homo sapiens	80-85	
3874094-4	1985	Our studies support the hypothesis that MPTP is oxidized in primate brain by MAO B to MPDP+, which is then converted to MPP+, a major metabolite found in the substantia nigra.	1-methyl-4-phenyl-2,3-dihydropyridinium	86-91	monoamine oxidase B	Homo sapiens	77-82