PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34521450-0 2021 Gut microbiota mediated the therapeutic efficacies and the side effects of prednisone in the treatment of MRL/lpr mice. Prednisone 75-85 Fas (TNF receptor superfamily member 6) Mus musculus 110-113 34521450-4 2021 Then, this study used fecal microbiota transplantation (FMT) to transfer the gut microbiota of prednisone-treated MRL/lpr mice into the blank MRL/lpr mice to reveal whether the gut microbiota regulated by prednisone had similar therapeutic efficiency and side effects as prednisone. Prednisone 95-105 Fas (TNF receptor superfamily member 6) Mus musculus 118-121 34521450-5 2021 RESULTS: The effects of prednisone on gut microbiota were dose-dependent in the treatment of MRL/lpr mice. Prednisone 24-34 Fas (TNF receptor superfamily member 6) Mus musculus 97-100 34521450-6 2021 After transplantation into MRL/lpr mice, prednisone-regulated gut microbiota could alleviate lupus, which might be due to decreasing Ruminococcus and Alistipes and retaining the abundance of Lactobacillus. Prednisone 41-51 Fas (TNF receptor superfamily member 6) Mus musculus 31-34 35514318-3 2022 Reduced expression of CD138 in DN T cells induced by prednisone treatment alleviated the accumulation of DN T cells in MRL/lpr mice. Prednisone 53-63 Fas (TNF receptor superfamily member 6) Mus musculus 123-126 35514318-2 2022 Accumulation of CD138+ T cells in the spleen of MRL/lpr mice was significantly reduced by prednisone. Prednisone 90-100 Fas (TNF receptor superfamily member 6) Mus musculus 52-55 35514318-4 2022 The frequency of CD138+ cells in CD4+ T cells of prednisone-treated MRL/lpr mice was also significantly reduced, which subsequently contributed to reduced production of anti-dsDNA antibody in the prednisone-treated MRL/lpr mice. Prednisone 49-59 Fas (TNF receptor superfamily member 6) Mus musculus 72-75 35514318-4 2022 The frequency of CD138+ cells in CD4+ T cells of prednisone-treated MRL/lpr mice was also significantly reduced, which subsequently contributed to reduced production of anti-dsDNA antibody in the prednisone-treated MRL/lpr mice. Prednisone 49-59 Fas (TNF receptor superfamily member 6) Mus musculus 219-222 35514318-4 2022 The frequency of CD138+ cells in CD4+ T cells of prednisone-treated MRL/lpr mice was also significantly reduced, which subsequently contributed to reduced production of anti-dsDNA antibody in the prednisone-treated MRL/lpr mice. Prednisone 196-206 Fas (TNF receptor superfamily member 6) Mus musculus 219-222 32346376-9 2020 Moreover, the short-term antibiotics or FMT before onset inhibited the therapeutic efficiency of prednisone on lupus from 9 to 13 weeks old of MRL/lpr mice. Prednisone 97-107 Fas (TNF receptor superfamily member 6) Mus musculus 147-150 30911862-5 2019 Treating MRL/lpr mice with prednisone (5 mg/kg) from the age of 8 weeks decreased anti-cardiolipin and anti-N-methyl-D-aspartate (NMDA) receptor antibody titres in the brain, reduced the weight of lymph nodes, and prolonged the floating latency in the forced swim test. Prednisone 27-37 Fas (TNF receptor superfamily member 6) Mus musculus 13-16 31786803-0 2020 Analysis of brain metabolites by gas chromatography-mass spectrometry reveals the risk-benefit concerns of prednisone in MRL/lpr lupus mice. Prednisone 107-117 Fas (TNF receptor superfamily member 6) Mus musculus 125-128 31118928-0 2019 Alterations of the Gut Microbiota Associated With Promoting Efficacy of Prednisone by Bromofuranone in MRL/lpr Mice. Prednisone 72-82 Fas (TNF receptor superfamily member 6) Mus musculus 107-110