PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31248333-3 2020 We present a case of a 41-year-old woman with a stable living-related kidney transplant maintained on an immunosuppressive regimen of cyclosporine, mycophenolate mofetil, and prednisone, who was subsequently diagnosed with a metastatic lobular breast carcinoma and papillary thyroid cancer and started palbociclib, a time-dependent CYP3A inhibitor. Prednisone 175-185 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 332-337 30737835-2 2019 Since prednisone is known to induce the cytochrome P450 iso-enzyme CYP3A4, which is the main metabolizing enzyme of docetaxel in the liver, a potential drug-drug interaction may occur. Prednisone 6-16 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 67-73 17925494-3 2007 The CYP3A4 pathway mediates the metabolism of a large number of drug entities, including the corticosteroids prednisone and prednisolone. Prednisone 109-119 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 4-10