PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34055544-10	2021	Steroid-sparing anti-interleukin-5 (IL-5) agents and dupilumab should be considered as alternative treatment options for patients, such as ours, with eosinophilic, prednisone-dependent asthma refractory to omalizumab therapy.	Prednisone	164-174	interleukin 5	Homo sapiens	36-40	
30217438-7	2018	Moreover, in comparison to the 6 months preceding the beginning of treatment with mepolizumab, after 24 weeks of anti-IL-5 therapy significant decreases were detected with regard to exacerbation numbers (from 3.64 +- 1.86 to 1.0 +- 0.78; p < 0.001) and oral intake of prednisone (from 24.11 +- 10.36 mg/day to 1.78 +- 3.82 mg/day).	Prednisone	271-281	interleukin 5	Homo sapiens	118-122	
33076829-7	2020	RESULTS: Dexamethasone suppressed the level of IL-5 and IL-13 mRNA within Th2 cells with ~ 10-fold higher potency than prednisolone (the active form of prednisone).	Prednisone	152-162	interleukin 5	Homo sapiens	47-51	
20568377-6	2010	After treatment, forced expiratory volume in 1 second significantly increased and sputum eosinophil percentages and IL-5 and IL-8 concentrations significantly decreased in the prednisone group, whereas no changes were observed in the placebo group.	Prednisone	176-186	interleukin 5	Homo sapiens	116-120	
25410844-7	2014	CONCLUSIONS: In patients with moderate-to-severe eosinophilic bronchitis, treatment with prednisone caused a significant reduction in sputum eosinophil counts, as well as in the sputum levels of IL-5 and ECP.	Prednisone	89-99	interleukin 5	Homo sapiens	195-199	
12722970-4	2003	RESULTS: The patient"s serum showed elevation of transforming growth factor beta1 and interleukin-5, which improved after treatment with low-dose prednisone.	Prednisone	146-156	interleukin 5	Homo sapiens	86-99	
11447379-8	2001	Prednisone treatment inhibited the appearance of mRNA, protein, or both for T(H)2 cytokines (IL-4 and IL-5), as well as for IL-2 and transforming growth factor alpha, but did not inhibit increases of immunoreactive GM-CSF in bronchoalveolar lavage fluid.	Prednisone	0-10	interleukin 5	Homo sapiens	102-106	
10836317-9	1999	Treatment with prednisone suppressed median sputum eosinophilia (from 16.3 to 0%, p<0.001), decreased sputum ECP (from 7,480 to 700 microg x L(-1), p = 0.01), but did not improve neutrophil numbers, fibrinogen or IL-5.	Prednisone	15-25	interleukin 5	Homo sapiens	216-220	
9812552-2	1997	The results revealed that after oral prednisone therapy, the serum IL-5, ECP levels and the numbers of peripheral blood eosinophils decreased, whereas the lung function significantly improved.	Prednisone	37-47	interleukin 5	Homo sapiens	67-71