PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35494533-2 2022 We report a 45-year-old man with non-small-cell lung cancer who developed hypophysitis 11 months after initiation of treatment with an anti-PD-L1/CTLA-4 bispecific antibody (KN046) that blocks both programmed death ligand-1 (PD-L1) and cytotoxic T-lymphocyte antigen-4 (CTLA-4), followed by regular oral replacement doses of prednisone and levothyroxine tablets. Prednisone 325-335 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 146-152 32246174-0 2020 The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade. Prednisone 20-30 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 123-129