PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21239635-2 2011 Treatment of diabetic rats with nitro-L-arginine methyl ester (L-NAME) to inhibit nitric oxide synthase or with tempol to reduce superoxide prevented these changes, suggesting the possibility that peroxynitrite (ONOO) may be the stimulus for the induction of renal COX-2 in diabetes. tempol 112-118 cytochrome c oxidase II, mitochondrial Rattus norvegicus 265-270 15879008-3 2005 Because oxidative stress is increased in diabetes and has been shown to induce COX-2, we assessed its contribution to prostaglandin release by treating diabetic rats with tempol (120 mg/kg/day) for 28 days. tempol 171-177 cytochrome c oxidase II, mitochondrial Rattus norvegicus 79-84 32909857-8 2021 Accordingly, increased COX-1 and COX-2 expressions by Ang II exposure were corrected by losartan, DPI, or tempol. tempol 106-112 cytochrome c oxidase II, mitochondrial Rattus norvegicus 33-38