PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24140862-5 2014 In vitro, confocal microscopy and size-exclusion chromatography demonstrated that dismutation of O2(-) by 4-hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl (Tempol) and decomposition of H2O2 by catalase prevented Hcys-induced aggregation of NLRP3 inflammasome proteins and inhibited Hcys-induced caspase-1 activation and IL-1beta production in mouse podocytes. tempol 154-160 caspase 1 Mus musculus 293-302 28633109-6 2017 This MR clustering was blocked by MR disruptor (MCD), ROS scavenger (Tempol) and TXNIP inhibitor (verapamil), accompanied by attenuation of 7-Keto or ChC-induced increase in caspase-1 activity. tempol 69-75 caspase 1 Mus musculus 174-183