PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30901719-6 2019 In addition, the elevated mRNA expression of MMP-1, MMP-3 and RAGE induced by TNBS was remarkably inhibited by BJOE, SASP or AZA treatments, while the mRNA expression of PPAR-gamma was significantly enhanced. Trinitrobenzenesulfonic Acid 78-82 peroxisome proliferator-activated receptor gamma Rattus norvegicus 170-180 25561788-12 2014 Fibrosis-related proteins such as phospho-p38, phospho-SMAD2/3, and PPARgamma were significantly higher in TNBS-treated rats compared to control rats (all P < 0.05). Trinitrobenzenesulfonic Acid 107-111 peroxisome proliferator-activated receptor gamma Rattus norvegicus 68-77 28990050-8 2017 Treatment with n-3 PUFA increased the gene expression of PPAR-gamma in TNBS-treated rats, and reduced the expression of NFAT, which ultimately reduced the release of IL-4 and IL-2 detected by RT-qPCR. Trinitrobenzenesulfonic Acid 71-75 peroxisome proliferator-activated receptor gamma Rattus norvegicus 57-67 28990050-10 2017 In conclusion, the present study demonstrated that dietary n-3 PUFA may attenuate experimental CD induced by TNBS in rats by regulating the expression and activity of the PPAR-gamma/NFAT signaling pathway. Trinitrobenzenesulfonic Acid 109-113 peroxisome proliferator-activated receptor gamma Rattus norvegicus 171-181 17343846-13 2007 A high expression of NF-kappaB p65 and p38 MAPK proteins appeared in colon mucosa from control TNBS-treated rats; nevertheless, PPARgamma agonist treatment drastically decreased them. Trinitrobenzenesulfonic Acid 95-99 peroxisome proliferator-activated receptor gamma Rattus norvegicus 128-137 19617644-12 2009 The protein expression for PPARgamma, which was down-regulated in rat colonic mucosa after exposure to TNBS as compared to that in intact colonic mucosa, was not significantly influenced by ghrelin treatment. Trinitrobenzenesulfonic Acid 103-107 peroxisome proliferator-activated receptor gamma Rattus norvegicus 27-36 16782535-14 2006 In summary, curcumin showed therapeutic effects on TNBS-induced colitis and the mechanisms by which curcumin exerts its effects may involve activation of PPARgamma and its ligands. Trinitrobenzenesulfonic Acid 51-55 peroxisome proliferator-activated receptor gamma Rattus norvegicus 154-163 15876425-13 2005 Our results also suggest that the activation of the PPARgamma pathway reduces COX-2 overexpression, returns the increased PGD(2) values to basal levels and induces a significant increase of TNBS-induced apoptosis. Trinitrobenzenesulfonic Acid 190-194 peroxisome proliferator-activated receptor gamma Rattus norvegicus 52-61