PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33100902-11 2020 Moreover, the expression of Ang II, ACE2, Ang (1-7), IL-17A, and IL-10 in the TNBS group increased compared to that in the control group. Trinitrobenzenesulfonic Acid 78-82 interleukin 10 Mus musculus 65-70 12457286-0 2002 IL-10 gene therapy prevents TNBS-induced colitis. Trinitrobenzenesulfonic Acid 28-32 interleukin 10 Mus musculus 0-5 10500069-7 1999 The protective role of IL-10 was demonstrated by the finding that neutralization of IL-10 in vivo using IL-10-specific antibodies inhibited the IL-2-IgG2b effects in TNBS-induced colitis. Trinitrobenzenesulfonic Acid 166-170 interleukin 10 Mus musculus 23-28 10500069-7 1999 The protective role of IL-10 was demonstrated by the finding that neutralization of IL-10 in vivo using IL-10-specific antibodies inhibited the IL-2-IgG2b effects in TNBS-induced colitis. Trinitrobenzenesulfonic Acid 166-170 interleukin 10 Mus musculus 84-89 10500069-7 1999 The protective role of IL-10 was demonstrated by the finding that neutralization of IL-10 in vivo using IL-10-specific antibodies inhibited the IL-2-IgG2b effects in TNBS-induced colitis. Trinitrobenzenesulfonic Acid 166-170 interleukin 10 Mus musculus 84-89 16306767-14 2005 A significant increase in IL-10, IFN-gamma, and PGE2 was noted in the Adex+TNBS group compared with the sham+TNBS group. Trinitrobenzenesulfonic Acid 75-79 interleukin 10 Mus musculus 26-31 12431903-9 2003 Schistosome egg exposure decreased colonic IFN-gamma but increased IL-10 mRNA expression in TNBS-treated mice. Trinitrobenzenesulfonic Acid 92-96 interleukin 10 Mus musculus 67-72 11777988-1 2002 In the present study, we define the relation between TGF-beta and IL-10 in the regulation of the Th1-mediated inflammation occurring in trinitrobenzene sulfonic acid (TNBS)-colitis. Trinitrobenzenesulfonic Acid 136-165 interleukin 10 Mus musculus 66-71 27600362-3 2016 Treatment with K17 also increased TNBS-suppressed expression of tight junction proteins and IL-10, but inhibited activation of nuclear factor-kappaB (NF-kappaB) and mitogen-activated protein kinases and expression of tumor necrosis factor alpha and IL-17. Trinitrobenzenesulfonic Acid 34-38 interleukin 10 Mus musculus 92-97 31112869-8 2019 Furthermore, they suppressed TNBS-induced expression of M1 macrophage markers TNF-alpha, CD80, CD86, and Arg2 expression while the expression of M2 macrophage markers Arg1, CD163, CD206, and IL-10 was induced. Trinitrobenzenesulfonic Acid 29-33 interleukin 10 Mus musculus 191-196 27579991-6 2017 The anti-inflammatory properties of erythropoietin in the TNBS-induced colitis were confirmed by suppression of pro-inflammatory mediators, such as TNF-alpha, IL-1beta and MPO, as well as a significant increase in the anti-inflammatory cytokine, IL-10, was promoted. Trinitrobenzenesulfonic Acid 58-62 interleukin 10 Mus musculus 246-251 27778057-5 2017 In the TNBS model was observed reduction in macroscopic and microscopic score, colon weight, neutrophil influx, IL-1beta, MIP-2 and keratinocyte chemoattractant (KC) levels, inhibition of adhesion molecules expression and restoration of IL-10 levels. Trinitrobenzenesulfonic Acid 7-11 interleukin 10 Mus musculus 237-242 29543509-6 2018 In the TNBS-induced colitis model, guggulsterone reduced disease activity index scores and TREM-1 expression, stimulated IL-10 production, and improved survival in wild-type mice. Trinitrobenzenesulfonic Acid 7-11 interleukin 10 Mus musculus 121-126 29545894-8 2018 In mesenteric lymph nodes, AdTGF-1 prevented the TNBS-induced reduction of Tregs and IL-10, and potentially increased the efficacy of dexamethasone. Trinitrobenzenesulfonic Acid 49-53 interleukin 10 Mus musculus 85-90 23375938-10 2013 Arctigenin inhibited TNBS-induced IL-1beta, TNF-alpha and IL-6 expression, as well as PI3K, AKT and IKKbeta phosphorylation and NF-kappaB activation in mice, but increased IL-10 and CD204 expression. Trinitrobenzenesulfonic Acid 21-25 interleukin 10 Mus musculus 172-177 26971225-5 2016 They also suppressed TNBS-induced Th17 cell differentiation and IL-17 expression, but increased TNBS-suppressed Treg cell differentiation and IL-10 expression. Trinitrobenzenesulfonic Acid 96-100 interleukin 10 Mus musculus 142-147 26926174-10 2016 In addition, neomangiferin inhibited TNBS-induced expression of tumor necrosis factor-alpha, IL-17, IL-6, and IL-1beta, and increased IL-10 expression. Trinitrobenzenesulfonic Acid 37-41 interleukin 10 Mus musculus 134-139 27761147-8 2016 Furthermore, these inhibited TNBS-induced T-bet, RORgammat, TNF-alpha, and IL-17 expression but increased TNBS-suppressed Foxp3 and IL-10 expression. Trinitrobenzenesulfonic Acid 106-110 interleukin 10 Mus musculus 132-137 25698557-6 2015 Oral administration of AIII and sarsasapogenin inhibited 2,3,4-trinitrobenzene sulfonic acid (TNBS)-induced colon shortening and myeloperoxidase activity in mice, along with reducing NF-kappaB activation and interleukin (IL)-1beta, tumor necrosis factor (TNF)-alpha, and IL-6 levels, while simultaneously increasing IL-10. Trinitrobenzenesulfonic Acid 94-98 interleukin 10 Mus musculus 316-321 25213465-10 2014 However, ursolic acid reversed TNBS-mediated downregulation of IL-10 expression to 79% of the normal control group (p < 0.05). Trinitrobenzenesulfonic Acid 31-35 interleukin 10 Mus musculus 63-68 24314293-0 2013 Effects of interleukin-4 or interleukin-10 gene therapy on trinitrobenzenesulfonic acid-induced murine colitis. Trinitrobenzenesulfonic Acid 59-87 interleukin 10 Mus musculus 28-42 24314293-8 2013 Injections of IL-4 or IL-10 significantly inhibited TNBS-induced colon tissue damage, disease activity index (DAI) and body weight loss compared to the control mice. Trinitrobenzenesulfonic Acid 52-56 interleukin 10 Mus musculus 22-27 24314293-11 2013 CONCLUSIONS: These data suggest that intraperitoneal injection of IL-4 or IL-10 plasmid was a potential strategy in control of TNBS-induced murine colitis, but their combination had less effect. Trinitrobenzenesulfonic Acid 127-131 interleukin 10 Mus musculus 74-79 27494685-7 2016 The expression of IL-2, TNF-alpha and IL-6 was significantly increased, whereas the expression of IL-10 was significantly decreased in the kappa-carrageenan+TNBS groups. Trinitrobenzenesulfonic Acid 157-161 interleukin 10 Mus musculus 98-103 23772040-7 2013 Finally, IL-10(+)CD8(+) T cells played a protective role in the TNBS-induced murine colitis model, indicating a critical role of this population of CD8(+) T cells in regulatory immune responses. Trinitrobenzenesulfonic Acid 64-68 interleukin 10 Mus musculus 9-14 22286041-3 2011 The aim of this paper was to evaluate the anti-inflammatory effect of the administration of milks fermented by Lactococcus lactis strains that produce IL-10 under the control of the xylose-inducible expression system using a trinitrobenzenesulfonic acid-induced colitis murine model. Trinitrobenzenesulfonic Acid 225-253 interleukin 10 Mus musculus 151-156 20828550-5 2010 Berberine inhibited colonic expression of iNOS, COX-2, IL-1beta, IL-6, and TNF-alpha, but increased IL-10 expression in the colons of TNBS-treated C3H/HeN and C3H/HeJ mice. Trinitrobenzenesulfonic Acid 134-138 interleukin 10 Mus musculus 100-105 19924809-8 2010 Serum LBP increased in WT mice following TNBS administration, in conjunction with increased serum TNF-alpha, IL-6, and IL-10, and expansion of regulatory T-cell numbers. Trinitrobenzenesulfonic Acid 41-45 interleukin 10 Mus musculus 119-124 18649083-9 2008 Further, the preventive transfer of wt or IL-10tg gammadelta T cells ameliorated TNBS-induced colitis resulting in prolonged survival and reduced histological damage (1.5+/-0.4 and 1.3+/-0.2, respectively vs. 3.8+/-0.3 in untransferred mice, p<0.05). Trinitrobenzenesulfonic Acid 81-85 interleukin 10 Mus musculus 42-47