PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22422925-4	2012	Extract of G. uralensis suppressed IL-6 and TNF-alpha production induced by lipid A moiety of LPS in RAW264.7 cells.	Lipid A	76-83	interleukin 6	Mus musculus	35-39	
22422925-5	2012	Among various G. uralensis-related components of saponins and flavanones/chalcones, GL and ILG could suppress IL-6 production induced by lipid A in dose-dependent manners in RAW264.7 cells.	Lipid A	137-144	interleukin 6	Mus musculus	110-114	
18173800-4	2008	In the assays using C3H/HeJ mouse cells, the LPS and native lipid A significantly stimulated splenocytes to cause mitosis, and peritoneal macrophages to induce tumor necrosis factor-alpha and interleukin-6 production.	Lipid A	60-67	interleukin 6	Mus musculus	192-205	
8156049-2	1994	LPS, synthetic Escherichia coli-type lipid A (compound 506) and tetraacyl precursor Ia (compound 406) inhibited the binding of 125I-LPS to macrophage-like J774.1 cells and induced the release of tumor necrosis factor alpha (TNF alpha) and interleukin 6 (IL-6).	Lipid A	37-44	interleukin 6	Mus musculus	239-252	
9467402-8	1997	Lipopolysaccharide and lipid A from S. sputigena both exhibited biological activity in activating the clotting enzyme of Limulus amebocytes, the Schwartzman reaction, mitogenicity for murine lymphocytes and in inducing interleukin-1 alpha and interleukin-6 production in murine macrophages to the same extent as those observed for lipopolysaccharide of the Salmonella serovar typhimurium used as a positive control.	Lipid A	23-30	interleukin 6	Mus musculus	243-256	
8156049-2	1994	LPS, synthetic Escherichia coli-type lipid A (compound 506) and tetraacyl precursor Ia (compound 406) inhibited the binding of 125I-LPS to macrophage-like J774.1 cells and induced the release of tumor necrosis factor alpha (TNF alpha) and interleukin 6 (IL-6).	Lipid A	37-44	interleukin 6	Mus musculus	254-258	
30656591-7	2019	However, IL-6, MCP-1, and TNF-alpha production induced by Pam3CSK4 or lipid A was not augmented when cells were pretreated with curdlan, a dectin-1 ligand, or mannan, a dectin-2 ligand.	Lipid A	70-77	interleukin 6	Mus musculus	9-13	
32698404-7	2020	In addition, Alcaligenes lipid A promoted antigen-specific T helper 17 (Th17) responses in the spleen; upregulated the expression of MHC class II, CD40, CD80, and CD86 on bone marrow-derived dendritic cells (BMDCs); enhanced the production of Th17-inducing cytokines IL-6 and IL-23 from BMDCs.	Lipid A	25-32	interleukin 6	Mus musculus	267-271	
30656591-8	2019	In contrast, pretreatment of cells with TLR ligands upregulated the production of IL-6 and TNF-alpha, but not MCP-1, induced by Pam3CSK4 or lipid A.	Lipid A	140-147	interleukin 6	Mus musculus	82-86