PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15450130-6 2004 In contrast, stimulation with LpA induced primarily time-independent and dose-independent production of IFN-gamma. Lipid A 30-33 interferon gamma Mus musculus 104-113 15778393-5 2005 Furthermore, the ability to overproduce TNF-alpha and IFN-gamma in response to LPS, lipid A, synthetic lipopeptide Pam(3)CysK(4), or whole killed bacteria was present in P. acnes-primed wild-type, but not TLR9(-/-), mice. Lipid A 84-91 interferon gamma Mus musculus 54-63 15663554-12 2004 After stimulation with LpA and ConA in vitro LP was increased and IFN-gamma concentration was decreased in SP-D(-/-) mice. Lipid A 23-26 interferon gamma Mus musculus 66-75 15193389-11 2004 The IFN-gamma release from splenocytes with Tat-coated nanoparticles was comparable to that from mice immunized with Tat and Lipid A, and 3.3-fold greater than that from mice immunized with Tat and Alum. Lipid A 125-132 interferon gamma Mus musculus 4-13 9234781-0 1997 Lipopolysaccharide and monophosphoryl lipid A differentially regulate interleukin-12, gamma interferon, and interleukin-10 mRNA production in murine macrophages. Lipid A 38-45 interferon gamma Mus musculus 86-103 10064056-2 1999 We found that high amounts of LPS, its lipid A moiety, and a lipid A analog all induced a decrease in IL-4 production and an increase in IFN-gamma production when given to keyhole limpet hemocyanin (KLH)-restimulated lymph node cells prepared from KLH-primed mice. Lipid A 39-46 interferon gamma Mus musculus 137-146 10064056-2 1999 We found that high amounts of LPS, its lipid A moiety, and a lipid A analog all induced a decrease in IL-4 production and an increase in IFN-gamma production when given to keyhole limpet hemocyanin (KLH)-restimulated lymph node cells prepared from KLH-primed mice. Lipid A 61-68 interferon gamma Mus musculus 137-146 10198602-0 1999 Monophosphoryl lipid A (MPL) upregulates major histocompatibility complex (MHC) class I expression by increasing interferon-gamma (IFN-gamma). Lipid A 15-22 interferon gamma Mus musculus 113-129 10198602-0 1999 Monophosphoryl lipid A (MPL) upregulates major histocompatibility complex (MHC) class I expression by increasing interferon-gamma (IFN-gamma). Lipid A 15-22 interferon gamma Mus musculus 131-140 8871602-0 1996 Reversal of age-related deficient influenza virus-specific CTL responses and IFN-gamma production by monophosphoryl lipid A. Lipid A 116-123 interferon gamma Mus musculus 77-86 8871602-5 1996 Coadministration of liposomal influenza vaccine with monophosphoryl lipid A (MPL) resulted in enhanced CD8+ CTL response and IFN-gamma production among old mice (35 and 12,000 times, respectively). Lipid A 68-75 interferon gamma Mus musculus 125-134 8136945-0 1994 Effects of tumor necrosis factor and dexamethasone on the regulation of interferon-gamma induction by monophosphoryl lipid A. Lipid A 117-124 interferon gamma Mus musculus 72-88 8683131-1 1996 AKR mouse peritoneal macrophages (PM) were previously found to have a defect in their response to lipid A for nitric oxide (NO)-mediated tumor cytotoxicity, which was related to a lower level of C1q synthesis and reconstituted by exogenous IFN-gamma or C1q. Lipid A 98-105 interferon gamma Mus musculus 240-249 7683323-6 1993 Distinct differences were also found between the mechanisms by which MIF and IFN-gamma synergized with lipid A for activation in that IFN-gamma-primed and lipid A triggered macrophages produced TNF and nitric oxide (NO), whereas MIF-primed cells did not. Lipid A 103-110 interferon gamma Mus musculus 134-143 7683323-6 1993 Distinct differences were also found between the mechanisms by which MIF and IFN-gamma synergized with lipid A for activation in that IFN-gamma-primed and lipid A triggered macrophages produced TNF and nitric oxide (NO), whereas MIF-primed cells did not. Lipid A 155-162 interferon gamma Mus musculus 77-86 2107257-5 1990 DHP-treated macrophages were inhibited in their response to direct activation and triggering of IFN-gamma-primed macrophages by lipid A, Poly I:C, and cobra venom factor for tumor cytotoxicity. Lipid A 128-135 interferon gamma Mus musculus 96-105 1907994-7 1991 Our results provide evidence that C1q modulates macrophage activation by lipid A for nitric oxide-mediated tumor cytotoxicity under the influence of IFN-gamma, which stimulates C1q synthesis and secretion. Lipid A 73-80 interferon gamma Mus musculus 149-158 3119714-0 1987 Lipid A-associated proteins provide an alternate "second signal" in the activation of recombinant interferon-gamma-primed, C3H/HeJ macrophages to a fully tumoricidal state. Lipid A 0-7 interferon gamma Mus musculus 98-114 31182297-9 2019 4) unique synergy mechanism between monophosphoryl lipid A (MPL A) and QS-21, formulated in a liposome (AS01) in the early IFN-gamma response, promoting vaccine immunogenicity. Lipid A 51-58 interferon gamma Mus musculus 123-132 20347630-3 2010 Herein, immunization of L(d) mice with HF10 (HPGSVNEFDF) with palmitic acid moieties or a monophosphoryl lipid A derivative elicited potent IFN-gamma production from L(d)-restricted CD8(+) T cells in vitro and protected mice. Lipid A 105-112 interferon gamma Mus musculus 140-149