PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22422925-7	2012	GL and ILG inhibited lipid A-induced NF-kappaB activation in Ba/F3 cells expressing TLR4/MD-2 and CD14 and BMMs.	Lipid A	21-28	CD14 antigen	Mus musculus	98-102	
33135636-3	2020	Here we show for first time that P2X7 receptor induces the release of CD14 in extracellular vesicles, resulting in a net reduction in macrophage plasma membrane CD14 that functionally affects LPS, but not monophosphoryl lipid A, pro-inflammatory cytokine production.	Lipid A	220-227	CD14 antigen	Mus musculus	70-74	
8613389-8	1996	Besides rough and smooth LPS, lipid A, heat-killed Escherichia coli, lipoteichoic acid, and Staphylococcus aureus cell wall extract (10 micrograms/ml) caused similar increases of mCD14.	Lipid A	30-37	CD14 antigen	Mus musculus	179-184	
16407172-1	2006	A cell surface receptor complex consisting of CD14, Toll-like receptor (TLR4), and MD-2 recognizes lipid A, the active moiety of lipopolysaccharide (LPS).	Lipid A	99-106	CD14 antigen	Mus musculus	46-50	
12065494-2	2002	When murine CD14 (mCD14), mTLR4, and mMD-2 were all expressed in human monocytic THP-1 cells, these cells were capable of responding to Salmonella lipid A.	Lipid A	147-154	CD14 antigen	Mus musculus	12-16	
12065494-2	2002	When murine CD14 (mCD14), mTLR4, and mMD-2 were all expressed in human monocytic THP-1 cells, these cells were capable of responding to Salmonella lipid A.	Lipid A	147-154	CD14 antigen	Mus musculus	18-23	
10064907-9	1999	LPS stimulation of p38 phosphorylation, NF-kappaB activation, and surface IgM expression were all blocked completely by lipid A-like endotoxin antagonists whether or not CD14 was present.	Lipid A	120-127	CD14 antigen	Mus musculus	170-174	
10064907-11	1999	Our data support the hypothesis that lipid A-mediated activation of cells requires stimulation of a putative lipid A sensor that is downstream of CD14, but upstream of p38 and NF-kappaB.	Lipid A	37-44	CD14 antigen	Mus musculus	146-150	
10064907-11	1999	Our data support the hypothesis that lipid A-mediated activation of cells requires stimulation of a putative lipid A sensor that is downstream of CD14, but upstream of p38 and NF-kappaB.	Lipid A	109-116	CD14 antigen	Mus musculus	146-150	
9767415-1	1998	Cytokine production induced via CD14-dependent and CD14-independent pathways was investigated in mouse peritoneal macrophages incubated with lipopolysaccharide (LPS) or lipid A.	Lipid A	169-176	CD14 antigen	Mus musculus	32-36	
9767415-5	1998	Lipid A stimulates cytokine synthesis through both CD14-dependent and CD14-independent mechanisms, but its action is weaker than that of LPS, indicating that the polysaccharide moiety may be necessary for proper stimulation of mouse macrophages by endotoxin.	Lipid A	0-7	CD14 antigen	Mus musculus	51-55	
9767415-5	1998	Lipid A stimulates cytokine synthesis through both CD14-dependent and CD14-independent mechanisms, but its action is weaker than that of LPS, indicating that the polysaccharide moiety may be necessary for proper stimulation of mouse macrophages by endotoxin.	Lipid A	0-7	CD14 antigen	Mus musculus	70-74	
20176798-7	2010	Accordingly, upon stimulation of HEK-293 cells with inactivated bacteria and purified endotoxin, lack of lipid A modification led to impaired NF-kappaB activation only when human, and not when murine, TLR4-MD-2-CD14 was expressed.	Lipid A	105-112	CD14 antigen	Mus musculus	211-215	
17114488-6	2006	Soluble CD14 is required for the sTLR4-stimulated increase of lipid A binding to sMD-2.	Lipid A	62-69	CD14 antigen	Mus musculus	8-12	
11545252-4	2001	METHODS: Cytokine release of interleukin (IL)-1, IL-6 and tumor necrosis factor-alpha from human monocytes via soluble CD14 (sCD14) or membrane-associated (mCD14) receptor using anti-CD14 monoclonal antibody (MEM-18) or lipid A structure (compound 406) was measured in bioassays.	Lipid A	220-227	CD14 antigen	Mus musculus	156-161	
10779788-4	2000	The hybrid molecule LL-10-H-14, containing endotoxin-binding domains from LALF and endotoxin-binding protein, turned out to be the most active peptide within the series of peptides tested here to inhibit the CD14/lipid A interaction and is able in vitro to block the endotoxin-induced TNF-alpha release of murine macrophages up to 90%.	Lipid A	213-220	CD14 antigen	Mus musculus	208-212