PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20336295-0 2010 Monophosphoryl lipid A plus IFNgamma maturation of dendritic cells induces antigen-specific CD8+ cytotoxic T cells with high cytolytic potential. Lipid A 15-22 CD8a molecule Homo sapiens 92-95 1831794-0 1991 Differential sensitivity of CD8+ suppressor and cytotoxic T lymphocyte activity to bacterial monophosphoryl lipid A. Lipid A 108-115 CD8a molecule Homo sapiens 28-31 1831794-1 1991 Treatment with a preparation of monophosphoryl lipid A, known to be capable of abolishing the expression of CD8+ suppressor T cell activity generated during the antibody response to type III pneumococcal polysaccharide (SSS-III), was found to have no adverse effect upon either induction or expression of CD8+ cytotoxic T lymphocyte activity specific for influenza A virus antigens. Lipid A 47-54 CD8a molecule Homo sapiens 108-111 1831794-1 1991 Treatment with a preparation of monophosphoryl lipid A, known to be capable of abolishing the expression of CD8+ suppressor T cell activity generated during the antibody response to type III pneumococcal polysaccharide (SSS-III), was found to have no adverse effect upon either induction or expression of CD8+ cytotoxic T lymphocyte activity specific for influenza A virus antigens. Lipid A 47-54 CD8a molecule Homo sapiens 305-308 1831794-2 1991 This suggests that suppressor T cells and cytotoxic T lymphocytes represent functionally distinct subsets of CD8+ T cells which can be differentiated on the basis of their sensitivities to inactivation by monophosphoryl lipid A. Lipid A 220-227 CD8a molecule Homo sapiens 109-112 21518876-0 2011 Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells. Lipid A 46-53 CD8a molecule Homo sapiens 119-122 10799875-0 2000 Monophosphoryl lipid A and QS21 increase CD8 T lymphocyte cytotoxicity to herpes simplex virus-2 infected cell proteins 4 and 27 through IFN-gamma and IL-12 production. Lipid A 15-22 CD8a molecule Homo sapiens 41-44 10799875-5 2000 CD8 cytotoxicity specific for HSV-2 IE proteins was enhanced by 48-67% when CD8 CTLs were coincubated with the combination of monophosphoryl lipid A and QS21 adjuvants at the time of Ag presentation. Lipid A 141-148 CD8a molecule Homo sapiens 0-3 10799875-5 2000 CD8 cytotoxicity specific for HSV-2 IE proteins was enhanced by 48-67% when CD8 CTLs were coincubated with the combination of monophosphoryl lipid A and QS21 adjuvants at the time of Ag presentation. Lipid A 141-148 CD8a molecule Homo sapiens 76-79