PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23620183-1	2013	We investigated the difference in the effect of synthetic lipid A compounds on MyD88-dependent and -independent Toll-like receptor 4 (TLR4) signaling in mouse macrophage cells.	Lipid A	58-65	myeloid differentiation primary response gene 88	Mus musculus	79-84	
23620183-3	2013	A maximum level of NF-kappaB activation, which is involved in IL-1beta gene transcription, was also induced to a similar level by these four lipid A compounds, while the maximum level of IFN-beta promoter activity induced during MyD88-independent signaling was also less than 50% for lipid IVa stimulation compared with other lipid A compounds.	Lipid A	141-148	myeloid differentiation primary response gene 88	Mus musculus	229-234	
21865549-9	2011	However, the MyD88-dependent and -independent pathways were impaired to the same extent, indicating that the adjuvant activity of monophosphorylated lipid A most likely arises from its decreased potential to induce an active receptor complex and not more downstream signaling events.	Lipid A	149-156	myeloid differentiation primary response gene 88	Mus musculus	13-18	
16424162-2	2006	In this study, we used a dual-tagging proteomic strategy to identify the components of the MyD88 signalosome in murine macrophages stimulated with lipid A.	Lipid A	147-154	myeloid differentiation primary response gene 88	Mus musculus	91-96	
27354411-0	2016	The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes.	Lipid A	66-73	myeloid differentiation primary response gene 88	Mus musculus	12-17	
15895089-2	2005	Macrophages from Heedless homozygotes signaled by the MyD88-dependent pathway in response to rough lipopolysaccharide (LPS) and lipid A, but not in response to smooth LPS.	Lipid A	128-135	myeloid differentiation primary response gene 88	Mus musculus	54-59	
25625178-0	2015	Hexa-acylated LPS-lipid A deploys the appropriate level of fibrin to confer protection through MyD88.	Lipid A	18-25	myeloid differentiation primary response gene 88	Mus musculus	95-100	
25389373-5	2014	The TLR4 agonist synthetic lipid A induced expression of TRIF-dependent genes at lower concentrations than were necessary to induce the expression of genes that depend on MyD88-mediated signaling.	Lipid A	27-34	myeloid differentiation primary response gene 88	Mus musculus	171-176	
25448706-4	2015	Compared with wild-type (WT) B cells, MyD88(-/-) B cells were markedly impaired in up-regulation of CD86 and proliferation induced by lipid A moiety of LPS.	Lipid A	134-141	myeloid differentiation primary response gene 88	Mus musculus	38-43