PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17785847-10 2007 Together, these observations constitute evidence for a role of the TRIF/IFN-beta pathway in the regulation of lipid A/TLR4-mediated endotoxin homotolerance. Lipid A 110-117 interferon beta 1, fibroblast Mus musculus 72-80 17581652-10 2007 It has also been found that isolated R. sin-1 LPS and lipid A agonize a mouse macrophage cell line to induce the production of TNF-alpha and interferon beta in a Toll-like receptor 4-dependent manner demonstrating species specific properties. Lipid A 54-61 interferon beta 1, fibroblast Mus musculus 141-156 23620183-3 2013 A maximum level of NF-kappaB activation, which is involved in IL-1beta gene transcription, was also induced to a similar level by these four lipid A compounds, while the maximum level of IFN-beta promoter activity induced during MyD88-independent signaling was also less than 50% for lipid IVa stimulation compared with other lipid A compounds. Lipid A 141-148 interferon beta 1, fibroblast Mus musculus 187-195 23620183-3 2013 A maximum level of NF-kappaB activation, which is involved in IL-1beta gene transcription, was also induced to a similar level by these four lipid A compounds, while the maximum level of IFN-beta promoter activity induced during MyD88-independent signaling was also less than 50% for lipid IVa stimulation compared with other lipid A compounds. Lipid A 326-333 interferon beta 1, fibroblast Mus musculus 187-195