PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30154209-2 2018 This complex process depends on transcriptional changes mediated by Ca2+-dependent NFAT signaling, mTOR-mediated signaling and increased activity of the guanine nucleotide biosynthetic inosine-5"-monophosphate (IMP) dehydrogenase 1 and 2 enzymes (IMPDH1 and IMPDH2, hereafter IMPDH). Inosine Monophosphate 185-209 inosine monophosphate dehydrogenase 1 Homo sapiens 247-253 1677450-5 1991 No change was noted in the intracellular concentration of the corresponding physiological deoxynucleoside-5"-triphosphate, dATP; positive correlation was observed, however, between the increase in ddATP formation from ddIno and the increase in intracellular IMP occurring as a consequence of IMPD inhibition. Inosine Monophosphate 258-261 inosine monophosphate dehydrogenase 1 Homo sapiens 292-296 2885446-3 1987 IMPD activity measured by the conversion of inosine monophosphate to xanthine monophosphate ranged from 12.5 to 87.0 (mean 49.4) pmol/h/10(6) cells in normal bone marrow. Inosine Monophosphate 44-65 inosine monophosphate dehydrogenase 1 Homo sapiens 0-4