PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2549385-6 1989 We now find that, in the presence of MgCl2, KCl, and inosine-5"-monophosphate as phosphate donor, purified cytosolic 5"-nucleotidase catalyzed the phosphorylation of ddlno. Inosine Monophosphate 53-77 5'-nucleotidase ecto Homo sapiens 117-132 1977386-4 1990 These results support the proposal that the initial phosphorylation of ddGuo is catalyzed by a phosphotransferase (5"-nucleotidase) which utilizes IMP as its phosphate donor (Johnson and Fridland, [1989] Molec. Inosine Monophosphate 147-150 5'-nucleotidase ecto Homo sapiens 115-130 2985697-2 1985 Inosine 5"-monophosphate first must be converted to inosine by the action of the enzyme ecto-5"-nucleotidase before it can be transported into the cell; inosine and hypoxanthine, however, can be transported directly. Inosine Monophosphate 0-24 5'-nucleotidase ecto Homo sapiens 88-108 2848805-5 1988 Soluble high Km 5"-nucleotidase is most active with IMP and GMP and their deoxy derivatives. Inosine Monophosphate 52-55 5'-nucleotidase ecto Homo sapiens 16-31 2848805-16 1988 These data show that: (a) soluble human placental high Km 5"-nucleotidase coexists in human placenta with the low Km enzyme; (b) under physiological conditions the enzyme favors the hydrolysis of IMP and is critically regulated by IMP, ATP, and Pi levels; and (c) kinetic properties of ATP and IMP are each modified by the other compound suggesting complex interaction of the associated binding sites. Inosine Monophosphate 196-199 5'-nucleotidase ecto Homo sapiens 58-73 6280893-0 1982 5"-Nucleotidase activity enhanced by manganese and magnesium ions with inosine monophosphate substrate. Inosine Monophosphate 71-92 5'-nucleotidase ecto Homo sapiens 0-15 6313843-0 1983 Continuous assay of serum 5-nucleotidase activity with inosine 5"-monophosphate as substrate and total automation using a transfer-analyzer (Kem-O-Mat). Inosine Monophosphate 55-79 5'-nucleotidase ecto Homo sapiens 26-40 6279335-2 1982 Inosine is formed by the hydrolysis of inosine 5"-monophosphate which is catalyzed by seric 5"-nucleotidase, and then is converted to hypoxanthine by nucleoside phosphorylase. Inosine Monophosphate 39-63 5'-nucleotidase ecto Homo sapiens 92-107 17174234-1 2006 BACKGROUND: Adenosine 5"-triphosphate is catabolized to adenosine 5"-monophosphate (AMP), which is further degraded by 2 pathways: deamination to inosine 5"-monophosphate and ammonia by AMP deaminase, or dephosphorylation to adenosine and inorganic phosphate by 5"-nucleotidase. Inosine Monophosphate 146-170 5'-nucleotidase ecto Homo sapiens 262-277 31401370-2 2019 In a previous study, it was suggested that single nucleotide polymorphisms (SNPs) in the ecto-5"-nucleotidase (NT5E) gene affect the concentration of IMP under postmortem conditions by regulating NT5E enzymatic activity in Japanese Black beef. Inosine Monophosphate 150-153 5'-nucleotidase ecto Homo sapiens 89-109 31401370-2 2019 In a previous study, it was suggested that single nucleotide polymorphisms (SNPs) in the ecto-5"-nucleotidase (NT5E) gene affect the concentration of IMP under postmortem conditions by regulating NT5E enzymatic activity in Japanese Black beef. Inosine Monophosphate 150-153 5'-nucleotidase ecto Homo sapiens 111-115 31401370-2 2019 In a previous study, it was suggested that single nucleotide polymorphisms (SNPs) in the ecto-5"-nucleotidase (NT5E) gene affect the concentration of IMP under postmortem conditions by regulating NT5E enzymatic activity in Japanese Black beef. Inosine Monophosphate 150-153 5'-nucleotidase ecto Homo sapiens 196-200 6255057-2 1980 In combination with the enzymes nucleoside phosphorylase and xanthine oxidase, inosine, formed by hydrolysis of 5"-IMP by 5"-nucleotidase, is cleaved phosphorolytically to hypoxanthine, which is oxidized to uric acid. Inosine Monophosphate 112-118 5'-nucleotidase ecto Homo sapiens 122-137 5775689-14 1969 After fractionation on Sephadex G-200 columns a single peak of 5"-nucleotidase activity (particle weight 120000-125000) was obtained with AMP, IMP and GMP as substrates. Inosine Monophosphate 143-146 5'-nucleotidase ecto Homo sapiens 63-78 23992315-11 2013 As for intracellular dephosphorylation of AMP, another intracellular 5"-nucleotidase, cN-I, is supposed to participate, because it hydrolyzes AMP more preferentially than IMP or GMP. Inosine Monophosphate 171-174 5'-nucleotidase ecto Homo sapiens 69-84 9675011-1 1998 Human 5"-nucleotidase (5"-NT, EC 3.1.3.5) is an enzyme that hydrolyzes nucleotides such as AMP or IMP (inosine 5"-monophosphate) into inorganic phosphate and the respective nucleoside. Inosine Monophosphate 98-101 5'-nucleotidase ecto Homo sapiens 6-21 9675011-1 1998 Human 5"-nucleotidase (5"-NT, EC 3.1.3.5) is an enzyme that hydrolyzes nucleotides such as AMP or IMP (inosine 5"-monophosphate) into inorganic phosphate and the respective nucleoside. Inosine Monophosphate 103-127 5'-nucleotidase ecto Homo sapiens 6-21 15699053-6 2005 Thus, phosphorylation of xanthosine by cytosolic 5"-nucleotidase circumvents the activity of IMP dehydrogenase, a rate-limiting enzyme, catalyzing the NAD(+)-dependent conversion of IMP to XMP at the branch point of de novo nucleotide synthesis, thus leading to the generation of guanine nucleotides. Inosine Monophosphate 93-96 5'-nucleotidase ecto Homo sapiens 49-64 8405663-2 1993 Low Km 5" nucleotidase purified from human seminal plasma has been used in this study to investigate the response of the enzyme ot adenine nucleoside di- and triphosphates in the presence of AMP and IMP as substrates. Inosine Monophosphate 199-202 5'-nucleotidase ecto Homo sapiens 7-22 1659319-1 1991 A cytosolic 5"-nucleotidase, acting preferentially on IMP and GMP, has been isolated from human colon carcinoma extracts. Inosine Monophosphate 54-57 5'-nucleotidase ecto Homo sapiens 12-27