PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32861775-5 2020 A database search indicated that this gene is the human cytosolic 5"-nucleotidase II gene (cN-II) homolog in Bombyx, which mediates the conversion of inosine monophosphate (IMP) to inosine, a precursor of uric acid. Inosine Monophosphate 150-171 5'-nucleotidase, cytosolic II Homo sapiens 91-96 32861775-5 2020 A database search indicated that this gene is the human cytosolic 5"-nucleotidase II gene (cN-II) homolog in Bombyx, which mediates the conversion of inosine monophosphate (IMP) to inosine, a precursor of uric acid. Inosine Monophosphate 173-176 5'-nucleotidase, cytosolic II Homo sapiens 91-96 22174667-5 2011 Amongst them, six compounds were predicted as better ligands than the natural substrate of cN-II, inosine 5"-monophosphate (IMP). Inosine Monophosphate 98-122 5'-nucleotidase, cytosolic II Homo sapiens 91-96 22132970-3 2011 As a member of the oxypurine cycle, cN-II is involved in the regulation of intracellular concentration of 5"-inosine monophosphate (IMP), 5"-guanosine monophosphate (GMP), and also 5-phosphoribose 1-pyrophosphate (PRPP) and is therefore involved in the regulation of purine and pyrimidine de novo and salvage synthesis. Inosine Monophosphate 106-130 5'-nucleotidase, cytosolic II Homo sapiens 36-41 22132970-3 2011 As a member of the oxypurine cycle, cN-II is involved in the regulation of intracellular concentration of 5"-inosine monophosphate (IMP), 5"-guanosine monophosphate (GMP), and also 5-phosphoribose 1-pyrophosphate (PRPP) and is therefore involved in the regulation of purine and pyrimidine de novo and salvage synthesis. Inosine Monophosphate 132-135 5'-nucleotidase, cytosolic II Homo sapiens 36-41 22174667-5 2011 Amongst them, six compounds were predicted as better ligands than the natural substrate of cN-II, inosine 5"-monophosphate (IMP). Inosine Monophosphate 124-127 5'-nucleotidase, cytosolic II Homo sapiens 91-96 18404470-1 2006 Cytosolic 5" nucleotidase II (cN-II) catalyses both the hydrolysis of a number of nucleoside monophosphates (e.g., IMP + H2O--> inosine + Pi), and the phosphate transfer from a nucleoside monophosphate donor to the 5" position of a nucleoside acceptor (e.g., IMP + guanosine --> inosine + GMP). Inosine Monophosphate 115-118 5'-nucleotidase, cytosolic II Homo sapiens 0-28 18404470-1 2006 Cytosolic 5" nucleotidase II (cN-II) catalyses both the hydrolysis of a number of nucleoside monophosphates (e.g., IMP + H2O--> inosine + Pi), and the phosphate transfer from a nucleoside monophosphate donor to the 5" position of a nucleoside acceptor (e.g., IMP + guanosine --> inosine + GMP). Inosine Monophosphate 262-265 5'-nucleotidase, cytosolic II Homo sapiens 0-28 18404470-1 2006 Cytosolic 5" nucleotidase II (cN-II) catalyses both the hydrolysis of a number of nucleoside monophosphates (e.g., IMP + H2O--> inosine + Pi), and the phosphate transfer from a nucleoside monophosphate donor to the 5" position of a nucleoside acceptor (e.g., IMP + guanosine --> inosine + GMP). Inosine Monophosphate 262-265 5'-nucleotidase, cytosolic II Homo sapiens 30-35 18404470-3 2006 It has been proposed that cN-II regulates the intracellular concentration of IMP and GMP and the production of uric acid. Inosine Monophosphate 77-80 5'-nucleotidase, cytosolic II Homo sapiens 26-31 18404470-1 2006 Cytosolic 5" nucleotidase II (cN-II) catalyses both the hydrolysis of a number of nucleoside monophosphates (e.g., IMP + H2O--> inosine + Pi), and the phosphate transfer from a nucleoside monophosphate donor to the 5" position of a nucleoside acceptor (e.g., IMP + guanosine --> inosine + GMP). Inosine Monophosphate 115-118 5'-nucleotidase, cytosolic II Homo sapiens 30-35 8641385-5 1996 In hyperthermia experiments a tumor-size-dependent, significant increase in the levels of the following catabolites has been demonstrated: [symbol: see text] [IMP + GMP] (sum of guanosine and inosine monophosphate levels), inosine, hypoxanthine, xanthine and uric acid, along with a drop in ATP and guanosine triphosphate (GTP) levels. Inosine Monophosphate 192-213 5'-nucleotidase, cytosolic II Homo sapiens 165-168 12916861-9 2003 Due to its phosphotransferase activity, cN-II can also phosphorylate inosine and 2",3"-dideoxyribonucleosides utilizing IMP as a phosphate donor. Inosine Monophosphate 120-123 5'-nucleotidase, cytosolic II Homo sapiens 40-45 8020339-1 1993 De novo synthesis precursors of the purine second messengers adenosine, guanosine and inosine are adenosine, guanosine and inosine monophosphate (AMP, GMP, IMP), respectively. Inosine Monophosphate 123-144 5'-nucleotidase, cytosolic II Homo sapiens 151-154