PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16757328-4	2006	The elevated sensitivity of IMP-depleted cells to ERK1/2 pathway activation suggests IMP acts as a signal threshold regulator by imposing reversible restrictions on the assembly of functional Raf/MEK/ERK kinase modules.	Inosine Monophosphate	28-31	mitogen-activated protein kinase kinase 7	Homo sapiens	196-199	
19091743-2	2009	IMP concentrations are directly regulated by Ras, through induction of autoubiquitination, to permit productive Raf-MEK complex assembly.	Inosine Monophosphate	0-3	mitogen-activated protein kinase kinase 7	Homo sapiens	116-119	
19091743-3	2009	Inhibition of Raf-MEK pathway activation by IMP occurs through the inactivation of KSR, a scaffold/adapter protein that couples activated Raf to its substrate MEK1.	Inosine Monophosphate	44-47	mitogen-activated protein kinase kinase 7	Homo sapiens	18-21	
18332145-2	2008	IMP concentrations are regulated by Ras through induction of autodegradation and can modulate signal/response thresholds by directly limiting the assembly of functional KSR1-dependent Raf.MEK complexes.	Inosine Monophosphate	0-3	mitogen-activated protein kinase kinase 7	Homo sapiens	188-191