PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31727535-4 2021 RESULTS: The CLP sepsis model induced AKI in C57/B6 mice; The expression of PD-1 and PD-L1 were increased in septic AKI mice; PD-1/PD-L1 induced apoptosis in T cells: the number of lymphocytes decreased by 64%, while the number of CD3+ T cells decreased by 27% compared with the sham group; Results also indicated that lactate up-regulates expression of PD-L1 in the kidney. Lactic Acid 319-326 hyaluronan and proteoglycan link protein 1 Mus musculus 13-16 30800000-6 2019 Based on a 1H NMR-based metabolomics analysis, CLP-induced septic mice had increased levels of acetate, pyruvate, and lactate in serum and decreased levels of alanine, aspartate, glutamate, and fumarate in lungs. Lactic Acid 118-125 hyaluronan and proteoglycan link protein 1 Mus musculus 47-50