PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35050463-5	2022	We have recently demonstrated that heat shock protein A12A (HSPA12A) inhibited renal cancer cell migration by suppressing lactate output and glycolytic activity, which were mediated by unstabilizing CD147 and promoting its degradation.	Lactic Acid	122-129	heat shock protein family A (Hsp70) member 12A	Homo sapiens	35-39	
35050463-5	2022	We have recently demonstrated that heat shock protein A12A (HSPA12A) inhibited renal cancer cell migration by suppressing lactate output and glycolytic activity, which were mediated by unstabilizing CD147 and promoting its degradation.	Lactic Acid	122-129	heat shock protein family A (Hsp70) member 12A	Homo sapiens	60-67	
35050463-7	2022	Extracellular acidification, lactate export, and glycolytic activity in HCC cells were also promoted following HSPA12A overexpression.	Lactic Acid	29-36	heat shock protein family A (Hsp70) member 12A	Homo sapiens	111-118	
35050463-8	2022	Further analysis revealed that HSPA12A interacted with MCT4 and increased its membrane localization, thereby promoting export of lactate generated from glycolysis; this led, ultimately, to HCC cell migration.	Lactic Acid	129-136	heat shock protein family A (Hsp70) member 12A	Homo sapiens	31-38	
32754264-0	2020	HSPA12A unstabilizes CD147 to inhibit lactate export and migration in human renal cell carcinoma.	Lactic Acid	38-45	heat shock protein family A (Hsp70) member 12A	Homo sapiens	0-7	
32754264-13	2020	Lactate export, glycolysis rate, and CD147 protein abundance were also inhibited by HSPA12A overexpression but promoted by HSPA12A knockdown.	Lactic Acid	0-7	heat shock protein family A (Hsp70) member 12A	Homo sapiens	84-91	
32754264-13	2020	Lactate export, glycolysis rate, and CD147 protein abundance were also inhibited by HSPA12A overexpression but promoted by HSPA12A knockdown.	Lactic Acid	0-7	heat shock protein family A (Hsp70) member 12A	Homo sapiens	123-130	
32754264-16	2020	Notably, the HSPA12A overexpression-induced inhibition of lactate export and migration were abolished by CD147 overexpression.	Lactic Acid	58-65	heat shock protein family A (Hsp70) member 12A	Homo sapiens	13-20	
32754264-18	2020	Overexpression of HSPA12A in RCC cells unstabilizes CD147 through increasing its ubiquitin-proteasome degradation, thereby inhibits lactate export and glycolysis, and ultimately suppresses RCC cell migration.	Lactic Acid	132-139	heat shock protein family A (Hsp70) member 12A	Homo sapiens	18-25