PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34919670-6 2022 IL-10 inhibits glucose uptake and glycolysis and promotes oxidative phosphorylation with lactate inhibition. Lactic Acid 89-96 interleukin 10 Homo sapiens 0-5 8945595-0 1996 Production of human tumor necrosis factor alpha, interleukin-6, and interleukin-10 is induced by lactic acid bacteria. Lactic Acid 97-108 interleukin 10 Homo sapiens 68-82 8537471-5 1995 In septic shock patients, interleukin-10 plasma levels were positively correlated with tumor necrosis factor (r = 0.8, p = 0.01) and with parameters of shock severity including lactate levels (r = 0.56, p < 0.05) and correlated negatively with blood platelet counts (r = -0.65, p < 0.05). Lactic Acid 177-184 interleukin 10 Homo sapiens 26-40 32290188-6 2020 Elevated concentrations of lactate and pyruvate in trained individuals correlated with enhanced levels of anti-inflammatory interleukin (IL)-10. Lactic Acid 27-34 interleukin 10 Homo sapiens 124-143 32290188-7 2020 In vitro validation experiments revealed that co-incubation with lactate and pyruvate enhances IL-10 production and attenuates the release of pro-inflammatory IL-1beta and IL-6 by LPS-stimulated leukocytes. Lactic Acid 65-72 interleukin 10 Homo sapiens 95-100 26675558-0 2016 Relationship Between Antiinflammatory Cytokine Interleukin-10 and Lactate Concentrations in Neonates Undergoing the Arterial Switch Operation. Lactic Acid 66-73 interleukin 10 Homo sapiens 47-61 30811636-8 2019 Lactate mediated part of the crosstalk between tumor cells and Mphis, promoting secretion of IL-1beta, IL-10, IL-6, and up-regulation of hypoxia induced factor-1alpha expression, and down-regulation of p65-NFkappaB phosphorylation in Mphis. Lactic Acid 0-7 interleukin 10 Homo sapiens 103-108 29567956-6 2018 These results indicate that functional lactic acid bacteria induce IL-6 and IL-10 production by dendritic cells, which contribute to upregulating the sIgA concentration at mucosal sites in humans. Lactic Acid 39-50 interleukin 10 Homo sapiens 76-81 26675558-1 2016 BACKGROUND: The aim of this study was to evaluate the relationship between antiinflammatory cytokine interleukin (IL)-10 production and perioperative lactate concentrations and their impact on postoperative outcomes in neonates undergoing the arterial switch operation (ASO). Lactic Acid 150-157 interleukin 10 Homo sapiens 101-120 26675558-9 2016 The strongest predictor of increased IL-10 on the first day after operation was a serum lactate level greater than 3 mmol/L measured after the surgical procedure on admission to the ICU, recording an odds ratio of 15.31. Lactic Acid 88-95 interleukin 10 Homo sapiens 37-42 26675558-11 2016 CONCLUSIONS: Elevated lactate levels are associated with increased IL-10 production on the first postoperative day. Lactic Acid 22-29 interleukin 10 Homo sapiens 67-72 25844698-16 2015 The interleukin-6/interleukin-10 ratio directly correlated with plasma lactate. Lactic Acid 71-78 interleukin 10 Homo sapiens 18-32 22664006-3 2012 The goal of the study was to determine the relationship between genetic polymorphisms in interleukin (IL)-10 (-1082G/A) or tumor necrosis factor (TNF)-alpha (-376 G/A) and lactate levels in patients during OLT surgery. Lactic Acid 172-179 interleukin 10 Homo sapiens 89-108 22664006-6 2012 RESULTS: Carriers of the IL-10/TNF-alpha genotype combination GG/GG showed significantly different changes in lactate levels at 1 hour after reperfusion and at the end of surgery. Lactic Acid 110-117 interleukin 10 Homo sapiens 25-30 22664006-10 2012 IL-10 (-1082G/A) and TNF-alpha (-376 G/A) gene polymorphisms could influence the variability of lactate levels after liver transplantation surgery. Lactic Acid 96-103 interleukin 10 Homo sapiens 0-5 16723241-1 2006 OBJECTIVE: Lactate levels after cardiac surgery are influenced by different proinflammatory (TNF, IL-6, IL-8) and anti-inflammatory (IL-10) cytokines. Lactic Acid 11-18 interleukin 10 Homo sapiens 133-138 16723241-2 2006 The goal of the study was to determine the relationship between polymorphism in the IL-10 (-1082G/A) and TNF-beta (+252G/A) genes and lactate levels in patients after cardiac surgery. Lactic Acid 134-141 interleukin 10 Homo sapiens 84-89 16723241-6 2006 RESULTS: No association was found between single polymorphism in IL-10 or TNF-beta gene and lactate levels, but the carriers of IL-10/TNF-beta genotype combination +A/GG had significantly different course of lactate levels in time with decrease in lactate (in comparison with increase in other groups) at 8h after the surgery. Lactic Acid 208-215 interleukin 10 Homo sapiens 128-133 16723241-6 2006 RESULTS: No association was found between single polymorphism in IL-10 or TNF-beta gene and lactate levels, but the carriers of IL-10/TNF-beta genotype combination +A/GG had significantly different course of lactate levels in time with decrease in lactate (in comparison with increase in other groups) at 8h after the surgery. Lactic Acid 208-215 interleukin 10 Homo sapiens 128-133 16723241-7 2006 CONCLUSIONS: IL-10 (-1082G/A) and TNF-beta (+252G/A) gene polymorphisms have a little, yet measurable influence on the time course of changes in lactate levels after cardiac surgery. Lactic Acid 145-152 interleukin 10 Homo sapiens 13-18 12078789-7 2002 Lactic acid levels after intensive care admission changed over time and were related to both TNF-beta and IL-10 G-1082A polymorphisms. Lactic Acid 0-11 interleukin 10 Homo sapiens 106-111 16297146-0 2005 Identification of strong interleukin-10 inducing lactic acid bacteria which down-regulate T helper type 2 cytokines. Lactic Acid 49-60 interleukin 10 Homo sapiens 25-39