PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34016793-0	2021	kappa-opioid receptor stimulation alleviates rat vascular smooth muscle cell calcification via PFKFB3-lactate signaling.	Lactic Acid	102-109	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Rattus norvegicus	95-101	
26498254-9	2015	Knockdown of PFKFB3 by siRNA transfection significantly inhibited reactive astrocyte proliferation and lactate release, an indicator of glycolysis.	Lactic Acid	103-110	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Rattus norvegicus	13-19	
26224098-6	2015	Additionally, we observed that FSH-stimulated lactate production was inhibited in the presence of a PFKFB3 inhibitor, revealing the physiological relevance of this mechanism.	Lactic Acid	46-53	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Rattus norvegicus	100-106