PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35359405-0 2022 Fbw7 Inhibits the Progression of Activated B-Cell Like Diffuse Large B-Cell Lymphoma by Targeting the Positive Feedback Loop of the LDHA/lactate/miR-223 Axis. Lactic Acid 137-144 microRNA 223 Homo sapiens 145-152 35359405-8 2022 Inversely, lactate negatively regulated Fbw7 via trigging the expression of miR-223, which targeted Fbw7 3"-UTR to inhibit its expression. Lactic Acid 11-18 microRNA 223 Homo sapiens 76-83 35359405-6 2022 In vitro and in vivo experiments were used to assess the effect of the Fbw7-mediated LDHA/lactate/miR-223 axis on DLBCL cells growth. Lactic Acid 90-97 microRNA 223 Homo sapiens 98-105 35359405-11 2022 Our study uncovers a negative functional loop consisting of a Fbw7-mediated LDHA/lactate/miR-223 axis, which may support the future ABC-DLBCL therapy by targeting LDHA-related inhibition. Lactic Acid 81-88 microRNA 223 Homo sapiens 89-96