PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31746077-0	2020	Lactate-fueled Oxidative Metabolism Drives DNMT1-mediated TAZ Activation.	Lactic Acid	0-7	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	58-61	
33097055-10	2020	Mechanistically, lactic acid coordinates TGF-beta1/Snail and TAZ/AP-1 pathway to induce formation of Snail/TAZ/AP-1 complex at the MRP1/ABCC1 promoter.	Lactic Acid	17-28	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	61-64	
33097055-10	2020	Mechanistically, lactic acid coordinates TGF-beta1/Snail and TAZ/AP-1 pathway to induce formation of Snail/TAZ/AP-1 complex at the MRP1/ABCC1 promoter.	Lactic Acid	17-28	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	107-110	
33097055-17	2020	The secreted lactic acid coordinates TGF-beta1/Snail and TAZ/AP-1 pathway to activate the expression of MRP1/ABCC1 protein, thus contributing to chemoresistance in NSCLC.	Lactic Acid	13-24	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	57-60	
31746077-3	2020	Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis-derived lactate efficiently increased TAZ expression and activity in lung cancer cells.	Lactic Acid	33-40	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	70-73	
31746077-3	2020	Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis-derived lactate efficiently increased TAZ expression and activity in lung cancer cells.	Lactic Acid	33-40	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	134-137	
31746077-3	2020	Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis-derived lactate efficiently increased TAZ expression and activity in lung cancer cells.	Lactic Acid	104-111	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	70-73	
31746077-3	2020	Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis-derived lactate efficiently increased TAZ expression and activity in lung cancer cells.	Lactic Acid	104-111	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	134-137	
31746077-5	2020	Upregulation of DNMT1 by lactate caused hypermethylation of TAZ negative regulator of LATS2 gene promoter, leading to TAZ activation.	Lactic Acid	25-32	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	60-63	
31746077-5	2020	Upregulation of DNMT1 by lactate caused hypermethylation of TAZ negative regulator of LATS2 gene promoter, leading to TAZ activation.	Lactic Acid	25-32	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	118-121	
34482375-8	2021	Increased level of extracellular lactate via Notch1/TAZ axis inhibited cytotoxic T-cell activity, leading to the invasive characteristic of lung cancer cells.	Lactic Acid	33-40	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	52-55	
28604752-0	2017	Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells.	Lactic Acid	19-26	tafazzin, phospholipid-lysophospholipid transacylase	Homo sapiens	35-38