PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3929786-0	1985	Metabolism of 1-naphthol by tyrosinase.	1-naphthol	14-24	tyrosinase	Homo sapiens	28-38	
3929786-1	1985	1-Naphthol was metabolized by the polyphenol oxidase, tyrosinase, primarily to 1,2-naphthoquinone and to small amounts of 1,4-naphthoquinone as well as to covalently bound products.	1-naphthol	0-10	tyrosinase	Homo sapiens	54-64	
3929786-3	1985	The activation by tyrosinase of 1-naphthol to covalently bound products suggested that it may alter the reaction kinetics of the enzyme.	1-naphthol	32-42	tyrosinase	Homo sapiens	18-28	
3929786-4	1985	This was investigated by studying the effects of 1-naphthol on the tyrosinase-catalysed oxidation of 4-hydroxyanisole.	1-naphthol	49-59	tyrosinase	Homo sapiens	67-77	
3929786-5	1985	Preincubation of tyrosinase with 1-naphthol increased the lag period of the oxidation of 4-hydroxyanisole, which may be due to a decrease in the amount of active enzyme, as well as to a reaction of 1-naphthol with 3,4-anisylquinone, an oxidation product of 4-hydroxyanisole.	1-naphthol	33-43	tyrosinase	Homo sapiens	17-27	
3929786-5	1985	Preincubation of tyrosinase with 1-naphthol increased the lag period of the oxidation of 4-hydroxyanisole, which may be due to a decrease in the amount of active enzyme, as well as to a reaction of 1-naphthol with 3,4-anisylquinone, an oxidation product of 4-hydroxyanisole.	1-naphthol	198-208	tyrosinase	Homo sapiens	17-27	
3929786-6	1985	The metabolic activation of 1-naphthol by tyrosinase to covalently bound species suggests that 1-naphthol or a structurally related derivative may be of potential therapeutic application in the treatment of cells high in tyrosinase activity, such as certain melanomas.	1-naphthol	28-38	tyrosinase	Homo sapiens	42-52	
3929786-6	1985	The metabolic activation of 1-naphthol by tyrosinase to covalently bound species suggests that 1-naphthol or a structurally related derivative may be of potential therapeutic application in the treatment of cells high in tyrosinase activity, such as certain melanomas.	1-naphthol	28-38	tyrosinase	Homo sapiens	221-231	
3929786-6	1985	The metabolic activation of 1-naphthol by tyrosinase to covalently bound species suggests that 1-naphthol or a structurally related derivative may be of potential therapeutic application in the treatment of cells high in tyrosinase activity, such as certain melanomas.	1-naphthol	95-105	tyrosinase	Homo sapiens	42-52	
3929786-6	1985	The metabolic activation of 1-naphthol by tyrosinase to covalently bound species suggests that 1-naphthol or a structurally related derivative may be of potential therapeutic application in the treatment of cells high in tyrosinase activity, such as certain melanomas.	1-naphthol	95-105	tyrosinase	Homo sapiens	221-231