PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33600815-8	2021	We found that LXA4 exerted protective effects on focal cerebral ischemia-reperfusion injury and reduced the expression of the pro-inflammatory cytokines IL-1beta and TNF-alpha.	lipoxin A4	14-18	tumor necrosis factor	Rattus norvegicus	166-175	
23063943-5	2012	LXA(4) also inhibited LPS-triggered apoptosis, activation of NF-kappaB, TNF-alpha and IL-8 mRNA and protein expression in TEV-1 cells.	lipoxin A4	0-5	tumor necrosis factor	Rattus norvegicus	72-81	
33760150-4	2021	LXA4 treatment attenuated PQ-induced lung injury, and this was accompanied by decreased tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta secretion levels, and reduced oxidative stress damage.	lipoxin A4	0-4	tumor necrosis factor	Rattus norvegicus	88-121	
31023998-10	2019	Intraperitoneal injection of LXA4 inhibited renal fibrosis by targeting TGF-ss/Smad signaling and downregulated serum TNF-alpha, IL-6, IL-8, and IFN-gamma in DN rats.	lipoxin A4	29-33	tumor necrosis factor	Rattus norvegicus	118-127	
17329090-1	2007	Studies have shown that lipoxin A(4) (LXA(4)) inhibited proliferation of mesangial cells in vitro induced by platelet-derived growth factor, epidermal growth factor, leukotriene D(4) or tumor necrosis factor-alpha.	lipoxin A4	24-33	tumor necrosis factor	Rattus norvegicus	166-213	
15954894-0	2005	Lipoxin A4 inhibits TNF-alpha-induced production of interleukins and proliferation of rat mesangial cells.	lipoxin A4	0-10	tumor necrosis factor	Rattus norvegicus	20-29	
15954894-12	2005	LXA(4) antagonized the phosphorylation of SHP-2 and activity of NF-kappaB induced by TNF-alpha.	lipoxin A4	0-5	tumor necrosis factor	Rattus norvegicus	85-94	
15954894-17	2005	TNF-alpha-induced decrement in expression of p27(kip1) protein was ameliorated by LXA(4) in a dose-dependent manner.	lipoxin A4	82-88	tumor necrosis factor	Rattus norvegicus	0-9