PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35411569-0	2022	Combination of resolvin E1 and lipoxin A4 promotes the resolution of pulpitis by inhibiting NF-kappaB activation through upregulating sirtuin 7 in dental pulp fibroblasts.	lipoxin A4	31-41	nuclear factor kappa B subunit 1	Homo sapiens	92-101	
31814225-5	2020	In addition, the effects of LXA4 were analyzed on the TLR-MyD88-NF-kappaB (TMN)-mediated intracellular signal pathway using immunocytochemistry.	lipoxin A4	28-32	nuclear factor kappa B subunit 1	Homo sapiens	64-73	
27887602-1	2016	It has been suggested that aspirin may be of benefit in treating sepsis and ARDS in view of its ability to block cyclo-oxygenase-1 (COX-1) and COX-2 activities; inhibit nuclear factor kappa B (NF-kappaB); enhance the production of endothelial nitric oxide (eNO) and lipoxin A4 (LXA4).	lipoxin A4	266-276	nuclear factor kappa B subunit 1	Homo sapiens	193-202	
30138965-0	2018	[Lipoxin A4 inhibits the invasion and migration of endometrial stromal cells by down-regulating NF-kappaB signaling-mediated autophagy].	lipoxin A4	1-11	nuclear factor kappa B subunit 1	Homo sapiens	96-105	
31200255-0	2019	15-epi-lipoxin A4 inhibits TNF-alpha-induced tissue factor expression via the PI3K/AKT/ NF-kappaB axis in human umbilical vein endothelial cells.	lipoxin A4	0-17	nuclear factor kappa B subunit 1	Homo sapiens	88-97	
31200255-6	2019	15-epi-LXA4 also inhibited the binding of NF-kappaB on the TF promoter, which is otherwise enhanced by TNF-alpha.	lipoxin A4	0-11	nuclear factor kappa B subunit 1	Homo sapiens	42-51	
31200255-8	2019	In conclusion, 15-epi-LXA4 lowered the TNF-alpha-induced high TF expression and activity by suppressing PI3K/AKT signaling activation, thereby reducing the binding capacity of NF-kappaB on the TF promoter in pc-HUVECs.	lipoxin A4	15-26	nuclear factor kappa B subunit 1	Homo sapiens	176-185	
24000382-7	2013	In conclusion, the protective effects of LXA4 to ALI may be executed through inhibition inflammation pathways of NF-kappaB and p38 MAPK and up-regulation of cytoprotective HO-1.	lipoxin A4	41-45	nuclear factor kappa B subunit 1	Homo sapiens	113-122	
25978361-14	2015	In conclusion, Simvastatin and benznidazole prevent endothelial activation induced by T. cruzi infection, and the effect of simvastatin is mediated by the inhibition of the NFkappaB pathway by inducing 15-epi-LXA4 production.	lipoxin A4	202-213	nuclear factor kappa B subunit 1	Homo sapiens	173-181	
21575454-11	2011	CONCLUSION: Our findings demonstrated that LXA(4) could prevent the endothelial cell hyperpermeability induced by LPS in HUVEC under which the possible mechanism was through inhibiting the expression of NF-kappaB and its related cytokines through receptor-dependent.	lipoxin A4	43-49	nuclear factor kappa B subunit 1	Homo sapiens	203-212