PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2835972-8	1988	We, therefore, conclude that cAMP mediates the inhibition of growth-related transformation-specific properties either by acting at steps subsequent to the expression of p21v-Ki-ras or on a pathway independent of p21ras function.	Cyclic AMP	29-33	Harvey rat sarcoma virus oncogene	Mus musculus	212-218	
7525612-0	1994	Ornithine decarboxylase gene expression is aberrantly regulated via the cAMP signal transduction pathway in malignant H-ras transformed cell lines.	Cyclic AMP	72-76	Harvey rat sarcoma virus oncogene	Mus musculus	118-123	
1647646-0	1991	Effect of vitamin E succinate and a cAMP-stimulating agent on the expression of c-myc and N-myc and H-ras in murine neuroblastoma cells.	Cyclic AMP	36-40	Harvey rat sarcoma virus oncogene	Mus musculus	100-105	
19167486-5	2009	BCR signaling to ERK1/2 and Akt requires cyclic AMP-regulated Epac, the latter acting as a guanine nucleotide exchange factor for Rap1 and H-Ras independent of protein kinase A.	Cyclic AMP	41-51	Harvey rat sarcoma virus oncogene	Mus musculus	139-144	
19167486-7	2009	Our data indicate that cyclic AMP-dependent Epac signals to ERK1/2 and Akt upon activation of Rap1 and H-Ras, and is involved in BCR-induced growth arrest and apoptosis in WEHI-231 cells.	Cyclic AMP	23-33	Harvey rat sarcoma virus oncogene	Mus musculus	103-108	
9393768-1	1997	The interplay between cyclic AMP (cAMP)-dependent protein kinase A (PKA)- and p21ras-mediated signaling pathways is expected to determine further loss, maintenance, or modulation of differentiation and proliferation of a particular cell.	Cyclic AMP	34-38	Harvey rat sarcoma virus oncogene	Mus musculus	78-84	
9078246-0	1997	cAMP suppresses p21ras and Raf-1 responses but not the Erk-1 response to granulocyte-colony-stimulating factor: possible Raf-1-independent activation of Erk-1.	Cyclic AMP	0-4	Harvey rat sarcoma virus oncogene	Mus musculus	16-22	
7505277-0	1994	Alterations in the cyclic AMP signal transduction pathway regulating ribonucleotide reductase gene expression in malignant H-ras transformed cell lines.	Cyclic AMP	19-29	Harvey rat sarcoma virus oncogene	Mus musculus	123-128	
7693388-0	1993	Cyclic AMP decreases chemotaxis, invasiveness and lung colonization of H-ras transformed mouse fibroblasts.	Cyclic AMP	0-10	Harvey rat sarcoma virus oncogene	Mus musculus	71-76	
2992503-0	1985	Two classes of cAMP analogs synergistically inhibit p21 ras protein synthesis and phenotypic transformation of NIH/3T3 cells transfected with Ha-MuSV DNA.	Cyclic AMP	15-19	Harvey rat sarcoma virus oncogene	Mus musculus	52-59	
3767986-1	1986	cAMP-dependent protein kinase activity in the soluble fraction was decreased in both v-H-ras-transformed and activated-c-H-ras-transformed NIH3T3 cells as compared with that in NIH3T3 cells.	Cyclic AMP	0-4	Harvey rat sarcoma virus oncogene	Mus musculus	87-92	
3767986-1	1986	cAMP-dependent protein kinase activity in the soluble fraction was decreased in both v-H-ras-transformed and activated-c-H-ras-transformed NIH3T3 cells as compared with that in NIH3T3 cells.	Cyclic AMP	0-4	Harvey rat sarcoma virus oncogene	Mus musculus	121-126	
3767986-2	1986	Both of the elution profile of type II cAMP-dependent protein kinase from DEAE-cellulose and the electrophoretic behavior of its regulatory subunits in the particulate fraction of H-ras-transformed cells are different from those of control NIH3T3 cells.	Cyclic AMP	39-43	Harvey rat sarcoma virus oncogene	Mus musculus	180-185	
2992503-3	1985	Treatment of cells with two classes of cAMP analogs which are selective for the two different cAMP-binding sites of type II protein kinase, in combination, synergistically inhibited both p21 ras protein synthesis and phenotypic transformation.	Cyclic AMP	39-43	Harvey rat sarcoma virus oncogene	Mus musculus	187-194	
2992503-3	1985	Treatment of cells with two classes of cAMP analogs which are selective for the two different cAMP-binding sites of type II protein kinase, in combination, synergistically inhibited both p21 ras protein synthesis and phenotypic transformation.	Cyclic AMP	94-98	Harvey rat sarcoma virus oncogene	Mus musculus	187-194	
29054855-7	2018	Genetic modulation studies in cardiomyocytes and cardiac and embryonic fibroblasts revealed that the lack of H-Ras down-regulates the B-RAF/MEK/ERK pathway, which induces the glycogen synthase kinase-3beta-dependent activation of the transcription factor, cAMP response element-binding protein, which is responsible for PKG-Ibeta overexpression in H -ras-/- mouse embryonic fibroblasts.	Cyclic AMP	256-260	Harvey rat sarcoma virus oncogene	Mus musculus	109-114