PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28826686-0	2017	Cofilin is a cAMP effector in mediating actin cytoskeleton reorganization and steroidogenesis in mouse and human adrenocortical tumor cells.	Cyclic AMP	13-17	cofilin 1	Homo sapiens	0-7	
28826686-2	2017	cAMP-induced steroidogenesis is preceded by actin cytoskeleton reorganization, a process regulated by cofilin activity.	Cyclic AMP	0-4	cofilin 1	Homo sapiens	102-109	
28826686-3	2017	In this study we investigated cofilin role in mediating cAMP effects on cell morphology and steroidogenesis in adrenocortical tumor cells.	Cyclic AMP	56-60	cofilin 1	Homo sapiens	30-37	
28826686-8	2017	Overall, these results identified cofilin as a mediator of cAMP effects on both morphological changes and steroidogenesis in mouse and human adrenocortical tumor cells.	Cyclic AMP	59-63	cofilin 1	Homo sapiens	34-41	
19339710-7	2009	Brief extraction of cytosolic proteins from living cells revealed that in cells treated with IL1B or cAMP (and SHs) for 6 days, cofilin was mainly detected in the nucleus.	Cyclic AMP	101-105	cofilin 1	Homo sapiens	128-135	
28062501-6	2017	In cultured VSMCs, we found that activation of P2Y12 receptor inhibited cAMP/protein kinase A signaling pathway, which induced cofilin dephosphorylation and filamentous actin disassembly, thereby enhancing VSMCs motility and migration.	Cyclic AMP	72-76	cofilin 1	Homo sapiens	127-134	
27328735-12	2016	Spontaneous myometrial contractility declined after 24 h but was less marked when tissues were constantly exposed to cAMP agonists, especially for 8-bromo-cAMP (4.3 +- 1.2 mean fold versus vehicle; P = 0.0043); this was associated with changes to calponin, cofilin and HSP20 phosphorylated/total protein levels.	Cyclic AMP	117-121	cofilin 1	Homo sapiens	257-264	
19339710-8	2009	The translocation of cofilin from cytosol to nucleus was also detected in HuFs treated for 12 days with SHs, IL1B and SHs, and cAMP and SHs.	Cyclic AMP	127-131	cofilin 1	Homo sapiens	21-28	
9410873-8	1997	In cells chemotactically activated with cyclic AMP, GFP-cofilin exhibits a high level of accumulation in projecting leading edges.	Cyclic AMP	40-50	cofilin 1	Homo sapiens	56-63	
16055445-0	2005	Myosin phosphatase and cofilin mediate cAMP/cAMP-dependent protein kinase-induced decline in endothelial cell isometric tension and myosin II regulatory light chain phosphorylation.	Cyclic AMP	39-43	cofilin 1	Homo sapiens	23-30