PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1689293-5 1990 In this report we show that several agents which raise intracellular cAMP (8-bromoadenosine 3":5"-cyclic monophosphate, 3-isobutyl-1-methylxanthine, cholera toxin, and prostaglandin E2) reversibly inhibit DNA synthesis in BMM induced by CSF-1, granulocyte macrophage-colony stimulating factor, interleukin-3, and PMA. Cyclic AMP 69-73 interleukin 3 Mus musculus 294-307 8062890-1 1994 We have reported modulation, by cytokines interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) and by hormonal cyclic-adenosine-monophosphate (cAMP) agonists, of hematopoietic growth factor production in the murine marrow adherent cell line +/+(-)1.LDA11. Cyclic AMP 165-169 interleukin 3 Mus musculus 184-211 2824613-16 1987 Finally, the observation that cholera toxin, prostaglandin E2, and N6,2"-O-dibutyryl adenosine 3",5"-cyclic monophosphate mimic the effects of IL-3 and GM-CSF on bone marrow cell HDC suggests an involvement of cyclic adenosine monophosphate in factor-induced histamine-producing cell-stimulating activity. Cyclic AMP 210-240 interleukin 3 Mus musculus 143-147 9885215-4 1999 cAMP dramatically increased ERK activity in the presence of CSF-1 or IL-3. Cyclic AMP 0-4 interleukin 3 Mus musculus 69-73 9885215-5 1999 IL-3 also synergized with cAMP to activate ERK in another myeloid cell line, FDC-P1. Cyclic AMP 26-30 interleukin 3 Mus musculus 0-4 9885215-7 1999 cAMP treatment of 32D cells transfected with oncogenic Ras was found to recapitulate the superactivation of ERK seen with cAMP and CSF-1 or IL-3. Cyclic AMP 0-4 interleukin 3 Mus musculus 140-144 9885215-10 1999 These findings suggest that upregulation of the ERK pathway is one mechanism induced by CSF-1 and IL-3 to protect myeloid progenitors from the growth-suppressive and apoptosis-inducing effects of cAMP elevations. Cyclic AMP 196-200 interleukin 3 Mus musculus 98-102 7636261-14 1995 The above results show that for mast cell induction, IL-3 needs the cooperation of PGE or other stimulants that can elevate the production of the second messenger cAMP in mast cell precursors. Cyclic AMP 163-167 interleukin 3 Mus musculus 53-57 2465166-6 1989 In initial experiments, cAMP levels in cells stimulated with either recombinant Epo or recombinant IL-3 were monitored. Cyclic AMP 24-28 interleukin 3 Mus musculus 99-103