PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17906691-4 2008 Pharmacological activation of the R2 subunits by the cAMP analogue 8-Cl-cAMP inhibited proliferation and increased caspase-3 activity by 68.77+/-10.5 and 72+/-9% respectively, in all cell lines with the exception of the only p53-mutated one. 8-chloro-cyclic adenosine monophosphate 53-57 tumor protein p53 Homo sapiens 225-228 18060599-9 2008 The initial resistance to IR-induced apoptosis in these p53-deficient prostate cancer cell lines was overcome through an alternative proapoptotic pathway induced by 8-Cl-cAMP. 8-chloro-cyclic adenosine monophosphate 165-174 tumor protein p53 Homo sapiens 56-59 17906691-4 2008 Pharmacological activation of the R2 subunits by the cAMP analogue 8-Cl-cAMP inhibited proliferation and increased caspase-3 activity by 68.77+/-10.5 and 72+/-9% respectively, in all cell lines with the exception of the only p53-mutated one. 8-chloro-cyclic adenosine monophosphate 67-76 tumor protein p53 Homo sapiens 225-228